Hepatitis C Viral RNA Genotype Test
Understanding Hepatitis C Genotyping
The Hepatitis C Viral RNA Genotype Test represents a breakthrough in precision medicine for managing chronic Hepatitis C virus (HCV) infections. This sophisticated molecular diagnostic tool plays a pivotal role in modern hepatology by identifying specific HCV genotypes, which directly influences treatment selection and duration. With over 70 million people worldwide affected by chronic HCV, accurate genotyping has become essential for developing personalized therapeutic approaches that maximize cure rates while minimizing side effects.
What the Test Measures and Detects
This advanced Real-Time PCR-based assay specifically targets and amplifies Hepatitis C viral RNA to determine the exact genetic strain infecting the patient. The test identifies:
- HCV Genotypes 1 through 6 and their subtypes
- Viral genetic variations that influence drug susceptibility
- Specific nucleotide sequences that determine treatment response
- Genetic markers associated with treatment resistance
Technical Specifications
The test utilizes cutting-edge Real-Time PCR technology with exceptional sensitivity, capable of detecting as few as 15 IU/mL of HCV RNA. Sample requirements include 2 mL (1 mL minimum) serum from SST tubes or 2 mL plasma from EDTA tubes, with proper refrigeration or freezing during transport to maintain RNA integrity.
Who Should Consider This Test
Several patient populations benefit significantly from HCV genotyping:
- Newly Diagnosed HCV Patients: Individuals with confirmed Hepatitis C infection requiring treatment planning
- Patients with Elevated Liver Enzymes: Those showing ALT/AST abnormalities without clear etiology
- Treatment-Naive Individuals: Patients preparing for their first HCV therapy regimen
- Previous Treatment Failures: Individuals who did not respond to earlier antiviral treatments
- High-Risk Populations: People with history of blood transfusions, IV drug use, or healthcare exposure
Symptoms and Clinical Indicators
Patients experiencing fatigue, jaundice, abdominal discomfort, or unexplained weight loss should discuss HCV testing with their healthcare provider. Those with known risk factors or abnormal liver function tests represent ideal candidates for comprehensive HCV evaluation including genotyping.
Benefits of Hepatitis C Genotype Testing
Undergoing HCV genotyping provides numerous clinical advantages:
- Personalized Treatment Selection: Different genotypes respond optimally to specific direct-acting antiviral regimens
- Optimized Treatment Duration: Genotype information helps determine whether 8, 12, or 16-week therapy is appropriate
- Improved Cure Rates: Genotype-guided therapy achieves sustained virologic response rates exceeding 95%
- Reduced Side Effects: Matching treatment to genotype minimizes unnecessary medication exposure
- Cost-Effective Care: Prevents wasted resources on ineffective treatments
- Enhanced Monitoring: Provides baseline for tracking treatment response and potential resistance
Understanding Your Test Results
Your HCV genotype results will typically indicate one of six major genotypes:
- Genotype 1: Most common in the United States (approximately 75% of cases)
- Genotype 2: Generally responds well to shorter treatment durations
- Genotype 3: May require more aggressive therapy and longer treatment
- Genotypes 4-6: Less common in the US but important for travel-related infections
Clinical Interpretation
Your gastroenterologist will interpret the genotype results in context of your overall health, liver function, and treatment history. Genotype 1 patients typically receive specific direct-acting antiviral combinations, while genotype 3 may require additional monitoring for steatosis. The absence of detectable HCV RNA indicates successful treatment response.
Test Pricing and Availability
| Test Name | Regular Price | Discount Price |
|---|---|---|
| Hepatitis C Viral RNA Genotype Test | $226 USD | $162 USD |
Turnaround Time and Sample Collection
We offer efficient testing with samples accepted Tuesday and Friday by 11 AM, with results available Thursday and Monday respectively. Proper sample handling is crucial – 12 hours of overnight fasting is recommended before collection, with serum or plasma separation within one hour of drawing.
Nationwide Accessibility
General Genetics Corporation provides comprehensive Hepatitis C testing services across the United States. Our state-of-the-art molecular diagnostics laboratories serve patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. With convenient locations and flexible scheduling, accessing precision HCV genotyping has never been easier.
Take Control of Your Liver Health Today
Don’t let Hepatitis C compromise your quality of life. Our Hepatitis C Viral RNA Genotype Test provides the critical information needed to develop an effective treatment strategy. With our discounted price of $162 USD, advanced molecular diagnostics are accessible to patients throughout the United States.
Ready to begin your journey to better liver health? Call our dedicated healthcare team at +1(267) 388-9828 to schedule your Hepatitis C genotyping test. Our experienced staff will guide you through the process and answer any questions about preparation, insurance coverage, and result interpretation.
Take the first step toward personalized Hepatitis C treatment – book your appointment today and benefit from our specialized molecular diagnostics expertise in liver disorder management.

