FLT3 Gene Mutation Test – Comprehensive Leukemia Genetic Analysis
Understanding FLT3 Gene Mutations in Acute Myeloid Leukemia
The FLT3 Gene Mutation Test represents a breakthrough in precision medicine for Acute Myeloid Leukemia (AML) patients. FLT3 (FMS-like tyrosine kinase 3) is a critical gene that regulates blood cell development and proliferation. When mutations occur in this gene, they can lead to uncontrolled cell growth and the development of aggressive leukemia forms. This specialized molecular diagnostic test provides essential information that directly influences treatment strategies and patient outcomes.
What Does the FLT3 Gene Mutation Test Detect?
Our advanced FLT3 Gene Mutation Test identifies specific genetic alterations that significantly impact AML prognosis and treatment response:
- Internal Tandem Duplications (ITD): The most common FLT3 mutation, occurring in approximately 25% of AML cases
- Tyrosine Kinase Domain (TKD) Mutations: Point mutations affecting the kinase domain, found in 5-10% of AML patients
- Mutation Burden Assessment: Quantitative analysis of mutation levels to guide treatment intensity
Who Should Consider FLT3 Gene Mutation Testing?
This test is particularly important for individuals with:
- Newly diagnosed Acute Myeloid Leukemia (AML)
- Relapsed or refractory AML cases
- Patients experiencing unexplained fatigue, bruising, or recurrent infections
- Individuals with abnormal blood counts requiring further investigation
- Patients being evaluated for targeted therapy options
Clinical Symptoms That May Indicate Need for Testing
- Persistent fatigue and weakness
- Unexplained bruising or bleeding
- Frequent infections
- Bone pain or tenderness
- Unintended weight loss
- Night sweats
Benefits of FLT3 Gene Mutation Testing
Undergoing FLT3 mutation analysis provides numerous clinical advantages:
- Personalized Treatment Planning: Identifies patients who may benefit from FLT3 inhibitor therapies
- Prognostic Information: Helps predict disease course and potential outcomes
- Treatment Response Monitoring: Enables tracking of mutation status during therapy
- Risk Stratification: Assists in determining appropriate treatment intensity
- Clinical Trial Eligibility: May qualify patients for targeted therapy trials
Understanding Your FLT3 Test Results
Our comprehensive report provides clear interpretation of your results:
- FLT3-ITD Positive: Indicates internal tandem duplication mutation, often associated with higher relapse risk
- FLT3-TKD Positive: Shows tyrosine kinase domain mutation, may respond to specific inhibitors
- Double Mutation: Presence of both ITD and TKD mutations requires specialized management
- Mutation Negative: No FLT3 mutations detected, suggesting standard treatment approaches
Next Steps Based on Results
Your oncologist will use these results to:
- Determine eligibility for FLT3 inhibitor medications
- Adjust chemotherapy intensity if needed
- Consider stem cell transplantation timing
- Monitor for emerging mutations during treatment
Test Information and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | FLT3 Gene Mutation Test |
| Discount Price | $150 USD |
| Regular Price | $176 USD |
| Turnaround Time | 1 Week |
| Sample Type | 5 mL (3 mL min.) whole blood / Bone marrow in 1 Lavender Top (EDTA) tube |
| Shipping Instructions | Ship refrigerated. DO NOT FREEZE |
| Required Documentation | Duly filled Genomics Clinical Information Requisition Form (Form 20) |
| Testing Methodology | Real Time PCR, Fragment Analysis |
Nationwide Testing Availability
GGC DNA provides comprehensive FLT3 Gene Mutation testing services across the United States. We have established testing facilities in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and Midwest locations
- Houston and Texas facilities
- Miami and Florida centers
- Seattle and Pacific Northwest locations
Why Choose GGC DNA for Your FLT3 Testing?
Our commitment to excellence includes:
- CLIA-certified laboratory facilities
- Board-certified molecular pathologists
- Rapid 1-week turnaround time
- Comprehensive genetic counseling support
- Direct communication with treating physicians
- Insurance pre-authorization assistance
Take Action for Your Health Today
Don’t delay this critical genetic testing. Early detection of FLT3 mutations can significantly impact your treatment success and long-term outcomes. Our team is ready to assist you with scheduling, sample collection, and result interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your FLT3 Gene Mutation Test. Our genetic specialists are available to answer your questions and guide you through the testing process. Take the first step toward personalized leukemia management with GGC DNA’s advanced molecular diagnostics.
