FISH Trisomy 21 Down Syndrome Test
Comprehensive Prenatal Genetic Screening for Chromosome 21 Abnormalities
The FISH Trisomy 21 Down Syndrome Test represents a breakthrough in prenatal genetic diagnostics, utilizing cutting-edge Fluorescence In Situ Hybridization (FISH) technology to provide rapid and accurate detection of Down syndrome. This specialized test targets chromosome 21 abnormalities with exceptional precision, delivering results within just 4 days to support informed decision-making during pregnancy.
What Does the FISH Trisomy 21 Test Detect?
This advanced diagnostic test specifically identifies numerical abnormalities involving chromosome 21, including:
- Trisomy 21 (Down syndrome) – the presence of three copies of chromosome 21
- Chromosome 21 mosaicism – mixed cell populations with normal and abnormal chromosome counts
- Translocation Down syndrome – when part of chromosome 21 attaches to another chromosome
Using fluorescent DNA probes that bind specifically to chromosome 21, our FISH technology provides visual confirmation of chromosomal status at the molecular level, offering superior accuracy compared to traditional screening methods.
Who Should Consider This Test?
The FISH Trisomy 21 Down Syndrome Test is recommended for expectant parents in the following situations:
- Advanced maternal age (35 years or older)
- Abnormal first or second trimester screening results
- Family history of chromosomal disorders
- Previous child with chromosomal abnormalities
- Abnormal ultrasound findings suggesting chromosomal issues
- Parental concern about genetic conditions
Key Benefits of FISH Technology
Choosing the FISH Trisomy 21 Test provides numerous advantages for prenatal care:
- Rapid Results: Receive comprehensive findings within 4 days instead of waiting weeks
- High Accuracy: 99% detection rate for Trisomy 21 with minimal false positives
- Early Detection: Identify chromosomal abnormalities early in pregnancy
- Targeted Analysis: Specific focus on chromosome 21 reduces unnecessary testing
- Minimal Risk: Non-invasive sample collection when using maternal blood
Understanding Your Test Results
Your FISH Trisomy 21 results will provide clear, comprehensive information:
- Normal Result: Two copies of chromosome 21 detected, indicating typical chromosomal pattern
- Abnormal Result: Three copies of chromosome 21 detected, suggesting Down syndrome
- Mosaic Pattern: Mixed cell populations requiring further evaluation
- Inconclusive Result: May require repeat testing or additional diagnostic procedures
Our genetic counselors provide detailed explanations of your results and discuss next steps, ensuring you have complete understanding and support throughout the process.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| FISH Trisomy 21 Down Syndrome Test | $150 USD | $188 USD |
Nationwide Testing Network
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and Midwest regions
- Houston and Texas metropolitan areas
- Phoenix and Southwest territories
- All other major US cities and regions
Our sample collection centers operate with extended hours, accepting samples daily until 4:00 PM to accommodate your schedule. Turnaround time for results is consistently 4 days from sample receipt.
Sample Requirements and Preparation
For optimal testing accuracy, please provide one of the following sample types:
- 5 mL (3 mL minimum) whole blood in 2 Green Top Sodium Heparin tubes
- Cord blood collection in appropriate containers
- 5 mL (3 mL minimum) amniotic fluid in sterile screw-capped containers
- 2 g Chorionic villus biopsy preserved in normal saline
Essential Documentation: Complete Chromosome & FISH Analysis Requisition Form (Form 17) and Prenatal Genetic Testing Consent Form (Form 18) must accompany all samples. Ship samples at 18-22°C for optimal preservation.
Take the Next Step in Prenatal Care
Don’t leave your prenatal genetic screening to chance. The FISH Trisomy 21 Down Syndrome Test provides the clarity and confidence you need during this important time. Our expert team of genetic specialists and counselors are ready to support you through every step of the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or discuss your testing options with our genetic counseling team.
Experience the peace of mind that comes with advanced genetic testing technology from GGC DNA – your trusted partner in prenatal diagnostics.
