FISH SRY Gene Test: Comprehensive Genetic Sex Determination Analysis
Understanding the FISH SRY Gene Test
The FISH SRY Gene Test represents a cutting-edge approach to genetic analysis, utilizing Fluorescence In Situ Hybridization (FISH) technology to detect the presence of the SRY (Sex-determining Region Y) gene. This specialized molecular diagnostic test provides essential information about genetic sex determination and plays a crucial role in identifying Y chromosome material in clinical scenarios where traditional methods may be insufficient.
The SRY gene, located on the Y chromosome, serves as the primary genetic switch for male sexual development. When present and functional, it initiates the cascade of events that lead to testis formation and subsequent male phenotypic development. Our FISH SRY Gene Test offers unparalleled accuracy in detecting this critical genetic marker, providing healthcare providers with reliable data for informed clinical decisions.
What the FISH SRY Gene Test Detects
This advanced genetic test specifically identifies and analyzes:
- Presence or absence of the SRY gene on the Y chromosome
- Y chromosome material in various genetic contexts
- Genetic markers for male sex determination
- Chromosomal abnormalities involving sex chromosomes
- Genetic basis for disorders of sexual development
The FISH methodology employed in this test uses fluorescently labeled DNA probes that bind specifically to the SRY gene region. When viewed under a fluorescence microscope, the presence of the SRY gene is indicated by distinct fluorescent signals, providing clear visual confirmation of genetic material.
Technical Specifications
- Methodology: Fluorescence In Situ Hybridization (FISH)
- Sample Type: 5 mL (3 mL minimum) whole blood from Green Top Sodium Heparin tube
- Shipping Requirements: Maintain at 18-22°C during transport
- Critical Note: DO NOT FREEZE samples
- Required Documentation: Duly filled Chromosome & FISH analysis Requisition Form (Form 17)
- Turnaround Time: Samples accepted daily by 4 pm; Reports delivered in 4 days
Who Should Consider the FISH SRY Gene Test
This specialized genetic test is particularly recommended for individuals presenting with:
Clinical Indications
- Ambiguous Genitalia: Newborns or infants with unclear physical sex characteristics
- Disorders of Sexual Development: Cases requiring precise genetic sex determination
- Suspected Sex Chromosome Abnormalities: Including Turner syndrome, Klinefelter syndrome, or mixed gonadal dysgenesis
- Infertility Evaluation: Males with unexplained infertility or abnormal sperm parameters
- Developmental Delays: When accompanied by physical features suggesting chromosomal abnormalities
- Family History: Individuals with family history of genetic sex determination disorders
Pediatric Applications
This test is especially valuable in pediatric genetics, where early and accurate diagnosis can significantly impact treatment planning and long-term outcomes. Pediatricians often recommend this test when:
- Physical examination reveals atypical genital development
- There’s discordance between phenotypic appearance and chromosomal sex
- Monitoring patients with known sex chromosome abnormalities
- Evaluating growth and developmental concerns
Benefits of the FISH SRY Gene Test
Choosing our FISH SRY Gene Test provides numerous advantages for patients and healthcare providers:
Clinical Benefits
- High Accuracy: FISH technology provides precise detection of the SRY gene with minimal false results
- Rapid Results: 4-day turnaround time enables timely clinical decision-making
- Comprehensive Analysis: Provides clear genetic information for sex determination
- Guidance for Treatment: Results inform appropriate medical and surgical interventions
- Family Counseling: Enables accurate genetic counseling for families
Patient-Centered Advantages
- Non-Invasive Sample Collection: Simple blood draw procedure
- Accessible Pricing: Affordable genetic testing with current discount
- Nationwide Availability: Testing available across all major US cities
- Expert Interpretation: Results analyzed by certified genetic specialists
- Insurance Support: Assistance with insurance pre-authorization when applicable
Understanding Your Test Results
Interpreting FISH SRY Gene Test results requires professional medical expertise, but here’s general guidance:
Possible Result Interpretations
- SRY Gene Present: Indicates presence of Y chromosome material and potential for male sexual development
- SRY Gene Absent: Suggests absence of Y chromosome material, typically associated with female genetic constitution
- Atypical Patterns: May indicate mosaicism, translocation, or other chromosomal rearrangements
- Technical Considerations: Rare technical failures may require repeat testing
Clinical Correlation
It’s essential to understand that genetic results must be correlated with clinical findings, physical examination, and other diagnostic tests. The presence of the SRY gene doesn’t guarantee typical male development, as other genetic and environmental factors influence sexual differentiation.
Next Steps After Testing
- Schedule follow-up consultation with your genetic specialist
- Discuss results in the context of complete clinical picture
- Consider additional testing if indicated
- Develop comprehensive management plan based on results
- Access genetic counseling services for family planning considerations
Test Pricing and Booking Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $184 |
| Regular Price | $204 |
Nationwide Testing Availability
We proudly serve patients across the United States with testing facilities in all major metropolitan areas including:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and Midwest regions
- Houston and Texas locations
- Phoenix and Southwest territories
- All other major US cities and regions
Take Action Today
Don’t delay crucial genetic testing that could provide answers for complex clinical situations. Our FISH SRY Gene Test offers reliable, accurate results with rapid turnaround times.
Ready to schedule your test? Contact our genetic specialists today to discuss your testing needs, verify insurance coverage, and schedule your appointment.
Book Your FISH SRY Gene Test Now
Call or WhatsApp: +1(267) 388-9828
Our genetic counseling team is available to answer your questions, explain the testing process, and help you schedule your appointment at a convenient location near you.
Take the first step toward genetic clarity and informed medical decision-making. Contact us today to learn more about how the FISH SRY Gene Test can provide the answers you need for optimal patient care.
