FISH PDGFR Beta 5q33 Gene Rearrangement Test
Comprehensive Genetic Analysis for Hematological Malignancies
The FISH PDGFR Beta 5q33 Gene Rearrangement Test represents a cutting-edge molecular diagnostic tool that plays a pivotal role in the accurate diagnosis and management of various blood cancers. This sophisticated cytogenetic analysis specifically targets the platelet-derived growth factor receptor beta (PDGFRB) gene located at chromosome 5q33, providing clinicians with essential information for developing targeted treatment strategies.
What Does This Test Measure?
The FISH PDGFR Beta 5q33 Gene Rearrangement Test detects specific genetic abnormalities involving the PDGFRB gene, including:
- Gene rearrangements and translocations involving PDGFRB
- Fusion genes resulting from chromosomal abnormalities
- Specific genetic markers associated with myeloproliferative neoplasms
- Molecular abnormalities that predict response to tyrosine kinase inhibitors
Who Should Consider This Test?
This specialized genetic test is recommended for individuals presenting with:
- Suspected chronic myelomonocytic leukemia (CMML)
- Unexplained eosinophilia or basophilia
- Myeloproliferative neoplasms with atypical features
- Patients with suspected 5q33 chromosomal abnormalities
- Individuals requiring targeted therapy assessment for hematological malignancies
- Cases where conventional cytogenetic testing reveals inconclusive results
Clinical Benefits and Importance
Undergoing the FISH PDGFR Beta 5q33 Gene Rearrangement Test offers numerous clinical advantages:
- Accurate Diagnosis: Provides definitive identification of specific genetic abnormalities
- Targeted Treatment Planning: Guides selection of appropriate tyrosine kinase inhibitors
- Prognostic Information: Helps predict disease progression and treatment response
- Personalized Medicine: Enables tailored therapeutic approaches based on genetic profile
- Monitoring Capabilities: Assists in tracking treatment effectiveness and disease evolution
Understanding Your Test Results
Your FISH PDGFR Beta 5q33 Gene Rearrangement Test results will provide critical information about your genetic profile:
- Positive Result: Indicates the presence of PDGFRB gene rearrangement, suggesting eligibility for targeted therapies
- Negative Result: No detectable PDGFRB rearrangement, requiring alternative diagnostic approaches
- Quantitative Analysis: Provides percentage of cells showing genetic abnormalities
- Clinical Correlation: Results should be interpreted in context with other clinical findings
Test Pricing Information
| Test Name | Discount Price | Regular Price |
|---|---|---|
| FISH PDGFR Beta 5q33 Gene Rearrangement Test | $150 USD | $188 USD |
Sample Requirements and Processing
For accurate testing, we require:
- 5 mL (3 mL minimum) whole blood OR 4 mL (2 mL minimum) Bone Marrow
- Collected in 2 Green Top (Sodium Heparin) tubes
- Ship at 18-22°C – DO NOT FREEZE
- Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory
- Samples accepted daily by 4 pm
- Results delivered within 4 working days
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Control of Your Health Today
Don’t wait to get the critical genetic information you need for proper diagnosis and treatment planning. Our experienced team of genetic specialists and hematologists are ready to assist you with comprehensive testing and personalized consultation.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your FISH PDGFR Beta 5q33 Gene Rearrangement Test and take the first step toward targeted, effective treatment.
Early detection and accurate genetic profiling can significantly impact treatment outcomes and quality of life. Trust our expertise in cytogenetic testing to provide the answers you need for informed medical decisions.
