FISH Multiple Myeloma with Positive Selection of CD138 Cells Test
Comprehensive Genetic Analysis for Multiple Myeloma Diagnosis
The FISH Multiple Myeloma with Positive Selection of CD138 Cells Test represents a cutting-edge approach to multiple myeloma diagnosis and management. This specialized genetic test combines fluorescence in situ hybridization (FISH) technology with advanced cell selection methods to provide highly accurate chromosomal analysis specifically targeting malignant plasma cells. By isolating CD138-positive cells, the test ensures that genetic abnormalities are detected exclusively in the cancerous plasma cell population, delivering unprecedented precision in multiple myeloma assessment.
What This Advanced Test Detects
Our comprehensive FISH analysis examines six critical genetic markers that play essential roles in multiple myeloma development and progression:
- Deletion 13q14.3: Identifies loss of chromosomal material associated with standard-risk disease
- Deletion 17p13.1: Detects TP53 gene deletion, indicating high-risk multiple myeloma
- Translocation t(11;14): Identifies CCND1/IGH fusion associated with cyclin D1 overexpression
- Translocation t(4;14): Detects FGFR3/IGH fusion linked to poor prognosis
- Translocation t(14;16): Identifies IGH/MAF fusion associated with aggressive disease
- Gain 1q: Detects amplification of chromosome 1q, a marker of disease progression
Who Should Consider This Essential Test
This specialized genetic analysis is recommended for individuals experiencing symptoms or clinical findings suggestive of multiple myeloma, including:
- Patients with unexplained bone pain, particularly in the back or ribs
- Individuals with persistent fatigue, weakness, or recurrent infections
- Those showing elevated protein levels in blood or urine tests
- Patients with abnormal kidney function or calcium levels
- Individuals with anemia without clear explanation
- Patients already diagnosed with multiple myeloma requiring risk stratification
- Those needing treatment response monitoring or disease progression assessment
Significant Benefits of Advanced Genetic Testing
Choosing the FISH Multiple Myeloma with CD138 Selection Test provides numerous advantages for patients and healthcare providers:
- Precise Risk Stratification: Accurately determines disease prognosis and guides treatment intensity
- Personalized Treatment Planning: Identifies specific genetic abnormalities that may respond to targeted therapies
- Early Detection of High-Risk Features: Identifies aggressive disease characteristics requiring intensive treatment
- Monitoring Disease Progression: Tracks genetic changes over time to assess treatment effectiveness
- Improved Diagnostic Accuracy: CD138 selection ensures analysis focuses specifically on malignant cells
- Comprehensive Genetic Profile: Provides complete picture of multiple myeloma genetics in a single test
Understanding Your Test Results
Our expert cytogenetics team provides detailed interpretation of your FISH Multiple Myeloma test results:
- Normal Results: No detected chromosomal abnormalities in the analyzed plasma cells
- Standard-Risk Abnormalities: Presence of t(11;14) or del(13q) typically indicates better prognosis
- High-Risk Abnormalities: Detection of del(17p), t(4;14), t(14;16), or gain(1q) suggests aggressive disease requiring intensive treatment
- Multiple Abnormalities: Presence of several genetic changes may indicate more complex disease biology
- Quantitative Assessment: Percentage of abnormal cells helps determine disease burden and monitor treatment response
All results are reviewed by board-certified specialists who provide clear explanations and clinical recommendations tailored to your specific genetic findings.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $412 |
| Regular Price | $626 |
Convenient Testing Across the United States
GGC DNA maintains comprehensive testing facilities throughout major US cities, ensuring accessible genetic testing services for patients nationwide. Our state-of-the-art laboratories process samples daily with a rapid turnaround time of just 4 working days from sample receipt. We accept bone marrow samples (preferred) or whole blood specimens, with detailed collection and shipping instructions provided upon scheduling.
Take Control of Your Multiple Myeloma Management
Don’t leave your multiple myeloma diagnosis and treatment planning to chance. Our advanced FISH testing with CD138 selection provides the genetic clarity needed for optimal disease management. With specialized expertise in oncology cytogenetics and cutting-edge technology, GGC DNA delivers the precision testing you deserve.
Ready to schedule your test? Contact our dedicated oncology testing specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward comprehensive multiple myeloma genetic analysis and personalized treatment planning.
