FISH BCL6 3q27 Gene Rearrangement Test
Comprehensive Genetic Analysis for Lymphoma Diagnosis
The FISH BCL6 3q27 Gene Rearrangement Test represents a cutting-edge approach to cancer diagnostics, specifically designed to detect chromosomal abnormalities in the BCL6 gene. This sophisticated genetic analysis plays a pivotal role in the accurate diagnosis and classification of various B-cell lymphomas, providing clinicians with critical information for developing targeted treatment strategies.
What Does This Test Measure?
The FISH BCL6 3q27 Gene Rearrangement Test specifically detects abnormalities in the BCL6 gene located on chromosome 3 at position q27. This gene encodes a transcriptional repressor protein that plays a crucial role in B-cell development and differentiation. When rearranged, the BCL6 gene can contribute to the development of lymphoma by disrupting normal cellular regulation processes.
- Detects specific chromosomal translocations involving the BCL6 gene
- Identifies gene rearrangements that conventional cytogenetics might miss
- Provides precise localization of genetic abnormalities
- Offers high-resolution analysis of chromosomal structure
Who Should Consider This Test?
This specialized genetic test is recommended for patients presenting with symptoms or clinical findings suggestive of B-cell lymphoma, particularly:
- Patients with unexplained lymph node enlargement
- Individuals experiencing persistent fatigue, night sweats, or unexplained weight loss
- Patients with abnormal blood counts or bone marrow findings
- Individuals with suspected or confirmed diffuse large B-cell lymphoma (DLBCL)
- Patients requiring precise lymphoma classification for treatment planning
- Cases where conventional diagnostic methods yield inconclusive results
Clinical Benefits and Applications
The FISH BCL6 3q27 Gene Rearrangement Test offers numerous advantages in clinical practice:
- Accurate Diagnosis: Provides definitive identification of specific genetic abnormalities associated with lymphoma
- Prognostic Information: Helps predict disease course and potential treatment response
- Treatment Guidance: Informs targeted therapy selection and treatment intensity decisions
- Monitoring Capability: Enables tracking of disease progression and treatment effectiveness
- High Sensitivity: Detects genetic abnormalities with exceptional precision
Understanding Your Test Results
Interpreting FISH BCL6 3q27 Gene Rearrangement Test results requires specialized expertise:
- Positive Result: Indicates the presence of BCL6 gene rearrangement, typically associated with specific lymphoma subtypes
- Negative Result: Suggests absence of detectable BCL6 rearrangement, though other genetic abnormalities may be present
- Quantitative Analysis: Results may include percentage of cells showing rearrangement, providing additional prognostic information
- Clinical Correlation: Results should always be interpreted in the context of clinical findings and other diagnostic tests
Your healthcare provider will discuss the specific implications of your test results and how they inform your treatment plan.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| FISH BCL6 3q27 Gene Rearrangement Test | $176 USD | $196 USD |
Nationwide Testing Availability
GGC DNA provides comprehensive FISH BCL6 3q27 Gene Rearrangement testing services across the United States. Our state-of-the-art laboratories and collection centers are conveniently located in major metropolitan areas including:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and the Midwest region
- Houston and Texas metropolitan areas
- Miami and Florida locations
- Philadelphia and Northeast regions
Sample Requirements and Processing
For accurate testing, please ensure proper sample collection and submission:
- Tissue Samples: Submit formalin-fixed paraffin-embedded tissue block containing minimum 10% tumor tissue
- Blood Samples: 4 mL (3 mL minimum) whole blood in Green Top (Sodium Heparin) tube
- Bone Marrow: 4 mL (2 mL minimum) bone marrow aspirate
- Shipping: Ship at room temperature (18-22°C), DO NOT FREEZE
- Required Documentation: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory
Turnaround Time: Samples accepted daily by 4 pm, with results typically available within 4 working days.
Take Control of Your Health Today
Don’t wait to get the answers you need for accurate diagnosis and effective treatment planning. Our team of genetic specialists and oncology experts are ready to provide you with comprehensive testing services and personalized support.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your FISH BCL6 3q27 Gene Rearrangement Test. Our knowledgeable staff will guide you through the testing process, answer your questions, and ensure you receive the highest quality genetic testing services available.
Early and accurate genetic testing can make a significant difference in your treatment journey. Trust GGC DNA for reliable, precise, and timely genetic analysis that empowers you and your healthcare team to make informed decisions about your care.
