FISH ALK1 Breakapart Rearrangement Test
Comprehensive Introduction to ALK Gene Testing
The FISH ALK1 Breakapart Rearrangement Test represents a cutting-edge molecular diagnostic approach that plays a pivotal role in modern oncology. This sophisticated genetic analysis detects specific chromosomal rearrangements involving the ALK (Anaplastic Lymphoma Kinase) gene, which serves as a critical biomarker for targeted cancer therapies. The test’s importance lies in its ability to identify patients who are likely to respond to ALK inhibitors, revolutionizing treatment outcomes for various malignancies.
What the Test Measures and Detects
This advanced FISH test specifically identifies:
- ALK gene rearrangements and translocations
- Chromosomal breakpoints within the ALK gene locus
- Fusion genes resulting from ALK rearrangements
- Specific genetic abnormalities that drive cancer progression
The test utilizes fluorescence in situ hybridization technology to visualize chromosomal structures and detect abnormal gene arrangements that conventional methods might miss.
Who Should Consider This Test
Clinical Indications and Symptoms
This test is recommended for patients presenting with:
- Newly diagnosed non-small cell lung cancer (NSCLC)
- Anaplastic large cell lymphoma (ALCL)
- Inflammatory myofibroblastic tumors
- Patients with advanced or metastatic cancer
- Individuals requiring targeted therapy selection
- Patients with treatment-resistant cancers
Significant Benefits of ALK Testing
Undergoing the FISH ALK1 Breakapart Rearrangement Test provides numerous advantages:
- Personalized Treatment Planning: Identifies patients eligible for ALK inhibitor therapies
- Improved Outcomes: Enables targeted treatments with higher response rates
- Reduced Side Effects: Avoids ineffective conventional chemotherapy
- Comprehensive Genetic Profiling: Provides detailed molecular characterization
- Timely Intervention: Rapid results facilitate prompt treatment decisions
Understanding Your Test Results
Interpretation Guidelines
Your test results will fall into one of these categories:
- Positive for ALK Rearrangement: Indicates the presence of ALK gene abnormalities, making you a candidate for targeted ALK inhibitor therapy
- Negative for ALK Rearrangement: No ALK abnormalities detected, suggesting alternative treatment approaches may be more appropriate
- Inconclusive Results: May require additional testing or sample collection
All results should be discussed with your oncologist or healthcare provider to determine the most appropriate treatment strategy based on your specific clinical situation.
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $300 |
| Regular Price | $450 |
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with branches conveniently located in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible, high-quality genetic testing services for patients throughout the country.
Schedule Your Test Today
Take the first step toward personalized cancer treatment. Our expert genetic counselors and oncology specialists are ready to assist you with comprehensive ALK testing and interpretation. Contact us now to schedule your FISH ALK1 Breakapart Rearrangement Test and receive the critical genetic information needed for optimal treatment planning.
Call or WhatsApp: +1(267) 388-9828
Our dedicated team is available to answer your questions, explain the testing process, and help you book your appointment at your convenience.
Testing Specifications
- Turnaround Time: Sample accepted daily by 4 pm; Results in 4 working days
- Sample Type: Formalin fixed paraffin embedded tissue block (must contain 10% tumor tissue)
- Shipping: Room temperature
- Required Documentation: Duly filled Chromosome & FISH analysis Requisition Form (Form 17)
