FISH 11q23 or LSI MLL Gene Breakapart Test
Comprehensive Genetic Analysis for Leukemia Diagnosis
The FISH 11q23 or LSI MLL Gene Breakapart Test represents a cutting-edge molecular diagnostic approach specifically designed to detect critical genetic rearrangements associated with hematological malignancies. This sophisticated cytogenetic analysis focuses on the MLL (Mixed Lineage Leukemia) gene located at chromosome band 11q23, which plays a pivotal role in leukemia development and progression.
What This Advanced Test Measures
This specialized FISH test precisely identifies:
- MLL gene rearrangements and translocations
- Chromosomal breakpoints at 11q23 region
- Gene fusion events involving MLL with various partner genes
- Specific genetic abnormalities driving leukemia pathogenesis
Clinical Indications: Who Should Consider This Test
This test is particularly recommended for patients presenting with:
- Suspected or confirmed acute myeloid leukemia (AML)
- Acute lymphoblastic leukemia (ALL) cases
- Unexplained cytopenias or abnormal blood counts
- Patients with previous leukemia history requiring monitoring
- Individuals with treatment-resistant hematological conditions
- Patients being evaluated for targeted therapy options
Significant Benefits of MLL Gene Testing
Undergoing the FISH 11q23 test provides multiple clinical advantages:
- Accurate Diagnosis: Precise identification of MLL rearrangements enables specific leukemia classification
- Prognostic Information: MLL abnormalities often correlate with specific disease outcomes and treatment responses
- Treatment Guidance: Results inform targeted therapy selection and intensity decisions
- Monitoring Capability: Enables tracking of minimal residual disease during treatment
- Comprehensive Assessment: Complements conventional cytogenetic analysis for complete genetic profiling
Understanding Your Test Results
Your FISH 11q23 test results will provide critical genetic information:
- Normal Result: No MLL gene rearrangement detected, suggesting standard risk classification
- Positive Rearrangement: Indicates MLL gene abnormality, often associated with specific leukemia subtypes
- Quantitative Analysis: Percentage of cells showing rearrangement helps assess disease burden
- Clinical Correlation: Results are interpreted in context of complete clinical presentation
All results are thoroughly reviewed by our board-certified cytogeneticists and hematopathologists to ensure accurate interpretation and clinical relevance.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $150 |
| Regular Price | $212 |
Nationwide Accessibility
General Genetics Corporation maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and Philadelphia. Our network ensures timely sample processing and rapid result delivery.
Take Action for Your Health
Don’t delay critical genetic testing that could significantly impact your leukemia diagnosis and treatment strategy. Our experienced team is ready to assist you with scheduling, sample collection, and result interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to book your FISH 11q23 MLL Gene Breakapart Test and take the first step toward precise leukemia diagnosis and personalized treatment planning.
Note: Sample collection available daily until 4 PM with results typically delivered within 4 working days. Required sample: 5 mL whole blood or 4 mL bone marrow in sodium heparin tubes. Proper completion of Chromosome & FISH analysis Requisition Form (Form 17) is mandatory for testing.
