Extractable Nuclear Antigens ENA Anti-Nuclear Antibodies ANA Quantitative Profile Test
Comprehensive Autoimmune Disorder Screening
The Extractable Nuclear Antigens ENA Anti-Nuclear Antibodies ANA Quantitative Profile Test represents a sophisticated diagnostic tool in modern immunopathology. This comprehensive screening evaluates the presence of specific autoantibodies that target nuclear antigens, providing crucial insights into various autoimmune connective tissue diseases. When the immune system mistakenly attacks the body’s own tissues, these antibodies serve as important biomarkers for accurate diagnosis and disease monitoring.
What This Test Measures and Detects
This advanced quantitative profile test specifically measures individual antibodies targeting key extractable nuclear antigens:
- Sm Antibody: Highly specific for systemic lupus erythematosus (SLE)
- U1RNP Antibody: Associated with mixed connective tissue disease
- SS-A/Ro Antibody: Linked to Sjögren’s syndrome and subacute cutaneous lupus
- SS-B/La Antibody: Often found in Sjögren’s syndrome patients
- Jo-1 Antibody: Marker for polymyositis and dermatomyositis
- Scl-70 Antibody: Specific for systemic sclerosis (scleroderma)
- Centromere Antibody: Associated with limited cutaneous systemic sclerosis
Who Should Consider This Test
This comprehensive autoimmune screening is recommended for individuals experiencing:
- Unexplained joint pain and swelling
- Persistent fatigue and malaise
- Characteristic skin rashes, particularly photosensitive rashes
- Dry eyes and dry mouth symptoms
- Muscle weakness and pain
- Raynaud’s phenomenon (color changes in fingers with cold exposure)
- Unexplained fever patterns
- Family history of autoimmune disorders
- Abnormal ANA test results requiring further characterization
Key Benefits of Taking This Test
- Early Disease Detection: Identify autoimmune conditions before significant tissue damage occurs
- Accurate Diagnosis: Differentiate between similar autoimmune disorders
- Treatment Guidance: Help physicians develop targeted treatment strategies
- Disease Monitoring: Track disease progression and treatment effectiveness
- Prognostic Information: Provide insights into disease severity and potential complications
- Comprehensive Screening: Evaluate multiple antibody markers in a single test
Understanding Your Test Results
Your quantitative ENA profile results will provide specific antibody levels measured through advanced Enzyme Immunoassay technology. Positive results for specific antibodies can indicate:
- Sm Antibody Positive: Strongly suggests systemic lupus erythematosus
- U1RNP Positive: May indicate mixed connective tissue disease
- SS-A/Ro Positive: Associated with Sjögren’s syndrome or subacute cutaneous lupus
- Scl-70 Positive: Suggests systemic sclerosis (scleroderma)
- Centromere Positive: Often seen in limited cutaneous systemic sclerosis
It’s important to note that test results should always be interpreted by a qualified healthcare provider in the context of your clinical symptoms and medical history. Some individuals may have positive antibodies without active disease, while others might have negative results despite having autoimmune conditions.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | Extractable Nuclear Antigens ENA Anti-Nuclear Antibodies ANA Quantitative Profile Test |
| Regular Price | $376 USD |
| Discount Price | $250 USD |
| Sample Type | 3 mL (1.5 mL min.) serum from 1 SST |
| Turnaround Time | Sample Tue/Fri by 9 am; Report Same Day |
| Method | Enzyme Immunoassay |
| Department | Immunopathology |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible autoimmune testing services for patients throughout the country.
Take Control of Your Health Today
Don’t let unexplained symptoms compromise your quality of life. Early detection and accurate diagnosis of autoimmune disorders can significantly improve treatment outcomes and prevent long-term complications. Our comprehensive ENA ANA Quantitative Profile Test provides the detailed information your healthcare provider needs to develop an effective management plan.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our experienced staff will guide you through the simple testing process and answer any questions you may have about autoimmune disorder screening.

