Cortisone Compound E 24-Hour Urine Test
Comprehensive Adrenal Function Analysis
The Cortisone Compound E 24-Hour Urine Test represents a sophisticated diagnostic approach to evaluating adrenal gland function and cortisol metabolism. This specialized test provides crucial insights into your body’s stress response system, hormonal balance, and overall endocrine health. By measuring cortisol levels in urine collected over a full 24-hour period, healthcare providers can obtain a comprehensive picture of adrenal activity that single blood tests cannot capture.
What This Test Measures and Detects
This advanced diagnostic assessment specifically measures:
- Free cortisol levels in urine over 24 hours
- Cortisone (Compound E) concentrations
- Creatinine levels to ensure collection accuracy
- Cortisol-to-cortisone ratios for metabolic assessment
The test utilizes cutting-edge Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) technology, providing unparalleled accuracy and specificity in hormone measurement. This methodology eliminates cross-reactivity issues common with traditional immunoassays, ensuring precise results for clinical decision-making.
Who Should Consider This Test
This comprehensive adrenal assessment is particularly valuable for individuals experiencing:
Symptoms of Adrenal Dysfunction
- Unexplained weight gain, particularly in the face and abdomen
- Persistent high blood pressure resistant to treatment
- Muscle weakness and fatigue that doesn’t improve with rest
- Mood changes, anxiety, or depression
- Irregular menstrual cycles in women
- Skin changes including thinning, bruising, or stretch marks
- Blood sugar fluctuations and insulin resistance
- Decreased libido and sexual function
Clinical Indications
- Suspected Cushing’s syndrome or disease
- Monitoring adrenal tumor treatment effectiveness
- Evaluating patients with osteoporosis at a young age
- Assessing unexplained metabolic syndrome components
- Pre-surgical evaluation for adrenal mass removal
Benefits of Taking the Cortisone Compound E Test
Comprehensive Diagnostic Insights
This test provides a complete 24-hour cortisol profile, offering significant advantages over single-point blood measurements. The extended collection period accounts for natural cortisol fluctuations throughout the day, providing a more accurate representation of adrenal function.
Advanced Technology Benefits
- LC-MS/MS methodology ensures highest accuracy
- Minimal interference from other compounds
- Precise measurement of both cortisol and cortisone
- Superior sensitivity for detecting subtle abnormalities
Clinical Decision Support
The results from this test enable healthcare providers to:
- Confirm or rule out adrenal disorders with confidence
- Monitor treatment effectiveness for adrenal conditions
- Guide appropriate therapeutic interventions
- Prevent unnecessary additional testing through comprehensive assessment
Understanding Your Test Results
Normal Range Interpretation
Normal cortisol levels in 24-hour urine typically range between 10-100 micrograms per 24 hours, though reference ranges may vary slightly between laboratories. Your healthcare provider will interpret results in the context of your specific symptoms, medical history, and other clinical findings.
Elevated Levels May Indicate
- Cushing’s syndrome or disease
- Adrenal tumors producing excess cortisol
- Pituitary gland abnormalities
- Ectopic ACTH production from other tumors
- Medication effects from corticosteroids
Low Levels May Suggest
- Adrenal insufficiency (Addison’s disease)
- Pituitary gland dysfunction
- Chronic steroid use leading to adrenal suppression
- Severe stress or illness affecting adrenal function
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $750 |
| Regular Price | $1000 |
Nationwide Testing Availability
We have testing centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible testing regardless of your location.
Collection Instructions and Timing
Sample Requirements
- Sample Type: 10 mL (5 mL minimum) aliquot of 24-hour urine
- Preservative: 10g boric acid in screw-capped container OR keep urine refrigerated during collection
- Documentation: Record 24-hour volume on test request form and specimen container
- Shipping: Refrigerated or frozen transport required
- Mandatory Form: Duly filled Test Send Out Consent Form (Form 35)
Turnaround Time
For optimal processing, submit samples by the 7th of the month. Results are typically available within 2-3 weeks after sample receipt, allowing for comprehensive analysis and quality assurance.
Take Control of Your Adrenal Health Today
Don’t let unexplained symptoms compromise your quality of life. The Cortisone Compound E 24-Hour Urine Test provides the comprehensive adrenal assessment needed for accurate diagnosis and effective treatment planning. Our experienced endocrinology specialists and advanced LC-MS/MS technology ensure you receive the most reliable results available.
Ready to understand your adrenal function? Book your test now or call our dedicated healthcare team at +1(267) 388-9828 to schedule your appointment. Take the first step toward better hormonal health and get the answers you deserve.
