BRAF Mutation Analysis Test
Understanding BRAF Mutation Analysis
The BRAF Mutation Analysis Test represents a breakthrough in precision medicine, offering critical insights into cancer genetics that directly influence treatment decisions. This advanced molecular diagnostic test examines the BRAF gene, which encodes a protein involved in regulating cell growth and division. When mutations occur in this gene, they can lead to uncontrolled cell proliferation and cancer development.
What Does the BRAF Mutation Analysis Test Measure?
This sophisticated genetic test specifically detects mutations in the BRAF gene, with particular focus on the V600E mutation and other clinically relevant variants. The test analyzes:
- BRAF V600E mutations – the most common oncogenic variant
- Other BRAF mutations including V600K, V600R, and V600D
- Genetic alterations that activate the MAPK signaling pathway
- Mutations that predict response to targeted BRAF inhibitors
Who Should Consider BRAF Mutation Testing?
BRAF mutation analysis is particularly important for individuals with:
- Diagnosed melanoma, especially advanced or metastatic cases
- Colorectal cancer with specific histological features
- Thyroid cancer, particularly papillary thyroid carcinoma
- Non-small cell lung cancer with specific characteristics
- Patients being considered for targeted therapy with BRAF inhibitors
- Individuals with treatment-resistant cancers requiring alternative approaches
Clinical Symptoms and Indications
Patients experiencing symptoms such as unexplained skin lesions, persistent cough, digestive issues, or abnormal growths should discuss BRAF testing with their oncologist. The test is especially valuable when:
- Standard treatments have shown limited effectiveness
- Cancer has progressed despite conventional therapy
- Personalized treatment options are being considered
- Clinical trial eligibility needs assessment
Benefits of BRAF Mutation Analysis
Undergoing BRAF mutation testing provides numerous advantages for cancer patients:
- Personalized Treatment Planning: Identifies patients who may benefit from targeted BRAF inhibitors
- Improved Treatment Outcomes: Enables selection of therapies with higher likelihood of success
- Reduced Side Effects: Helps avoid ineffective treatments and unnecessary toxicity
- Prognostic Information: Provides insights into disease progression and potential outcomes
- Clinical Trial Access: Opens doors to innovative treatment protocols
- Comprehensive Cancer Management: Supports multidisciplinary treatment approaches
Understanding Your Test Results
Your BRAF mutation analysis results will fall into one of several categories:
- BRAF Mutation Detected: Indicates the presence of a clinically significant BRAF mutation, potentially making you eligible for targeted therapies
- No BRAF Mutation Detected: Suggests that BRAF-targeted treatments may not be appropriate, guiding your oncologist toward alternative approaches
- Inconclusive Results: May require additional testing or sample collection
It’s essential to discuss your results with your healthcare provider, who can interpret them in the context of your specific cancer type, stage, and overall health status.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| BRAF Mutation Analysis Test | $200 USD | $300 USD |
Nationwide Accessibility
General Genetics Corporation provides comprehensive BRAF mutation testing services across the United States. We have established branches in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and the Midwest
- Houston and Texas medical centers
- Phoenix and Southwest regions
- Major medical hubs nationwide
Sample Requirements and Processing
For accurate BRAF mutation analysis, we require:
- Formalin-fixed paraffin-embedded tissue block with at least 10% tumor tissue
- Alternative: 3 mL whole blood from EDTA tube (minimum 2 mL)
- Properly completed NGS Test Requisition Form (Form 40)
- Sample submission by Tuesday 11:00 AM for Monday report delivery
Take Control of Your Cancer Treatment Journey
Don’t leave your treatment decisions to chance. The BRAF Mutation Analysis Test provides the genetic intelligence needed to make informed choices about your cancer care. Our experienced molecular diagnostics team ensures accurate, reliable results that your healthcare team can trust.
Ready to unlock personalized cancer treatment options? Call our dedicated genetics specialists today at +1(267) 388-9828 to schedule your BRAF Mutation Analysis Test. Our team is available to answer your questions and guide you through the testing process.
