Anti-Neutrophil Cytoplasmic Antibody ANCA Panel Serum Test
Comprehensive Diagnostic Testing for Autoimmune Vasculitis
The Anti-Neutrophil Cytoplasmic Antibody (ANCA) Panel Serum Test represents a cornerstone in modern autoimmune disease diagnostics, specifically designed to detect and characterize antibodies that target neutrophil cytoplasmic components. This sophisticated panel plays a critical role in identifying and differentiating various forms of autoimmune vasculitis, conditions where the body’s immune system mistakenly attacks its own blood vessels.
What Does the ANCA Panel Measure?
Our comprehensive ANCA Panel evaluates three essential components through advanced laboratory methodologies:
- ANCA Screening via Immunofluorescence Assay (IFA): Provides initial detection of cytoplasmic and perinuclear staining patterns
- ANCA-MPO (Myeloperoxidase) Antibodies via Enzyme Immunoassay: Specifically detects antibodies against myeloperoxidase enzyme
- ANCA-PR3 (Proteinase 3) Antibodies via Enzyme Immunoassay: Identifies antibodies targeting proteinase 3 enzyme
Who Should Consider ANCA Testing?
This test is particularly recommended for individuals experiencing symptoms that may indicate autoimmune vasculitis, including:
- Unexplained systemic symptoms such as persistent fever, fatigue, and weight loss
- Joint pain and swelling without clear cause
- Skin manifestations including rashes, ulcers, or purpura
- Respiratory symptoms like chronic sinusitis, nosebleeds, or breathing difficulties
- Kidney dysfunction evidenced by abnormal urinalysis or elevated creatinine
- Neurological symptoms including numbness, weakness, or vision changes
- Ear, nose, and throat symptoms that persist despite treatment
Clinical Benefits of ANCA Panel Testing
Early detection through ANCA testing provides numerous advantages for patient care:
- Accurate Diagnosis: Differentiates between various forms of vasculitis for targeted treatment
- Disease Monitoring: Helps track disease activity and treatment response over time
- Treatment Guidance: Informs appropriate immunosuppressive therapy decisions
- Prognostic Value: Certain antibody patterns correlate with disease severity and outcomes
- Prevention of Organ Damage: Early intervention can prevent irreversible damage to kidneys, lungs, and other organs
Understanding Your ANCA Test Results
Interpreting ANCA panel results requires careful consideration of clinical context:
- Positive c-ANCA with PR3 antibodies: Strongly associated with granulomatosis with polyangiitis (Wegener’s)
- Positive p-ANCA with MPO antibodies: Typically indicates microscopic polyangiitis or eosinophilic granulomatosis with polyangiitis
- Atypical patterns: May suggest drug-induced vasculitis or other autoimmune conditions
- Negative results: Do not completely rule out vasculitis, as some patients may be ANCA-negative
Your healthcare provider will correlate these laboratory findings with your clinical presentation, imaging studies, and other diagnostic tests to establish a comprehensive diagnosis.
Test Details and Pricing
| Test Component | Price (USD) |
|---|---|
| Test Name | Anti-Neutrophil Cytoplasmic Antibody ANCA Panel Serum Test |
| Discount Price | $162 |
| Regular Price | $250 |
| Sample Requirements | 3 mL (2 mL min.) serum from 1 SST |
| Turnaround Time | Same-day results by 6 PM when sample received by 9 AM |
| Sample Collection Days | Tuesday, Thursday, Saturday |
Nationwide Accessibility
General Genetics Corporation provides comprehensive ANCA testing services across the United States, with conveniently located branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing regardless of location.
Take Control of Your Health Today
Don’t let unexplained symptoms compromise your quality of life. Early detection of autoimmune vasculitis through ANCA testing can lead to more effective treatment and better long-term outcomes. Our experienced immunopathology specialists are ready to provide the diagnostic clarity you need.
Schedule your ANCA Panel Serum Test today by calling our dedicated healthcare line at +1(267) 388-9828 or book your appointment online. Take the first step toward accurate diagnosis and personalized treatment for autoimmune conditions.
