Amyloid Protein Identification Test
Comprehensive Amyloidosis Diagnosis and Characterization
The Amyloid Protein Identification Test represents a cutting-edge diagnostic approach for detecting and characterizing amyloid protein deposits in human tissues. Amyloidosis is a complex group of diseases characterized by the abnormal accumulation of misfolded proteins that form insoluble fibrils in various organs and tissues. This comprehensive testing methodology combines traditional histological techniques with advanced proteomic analysis to provide definitive identification of amyloid protein subtypes, enabling precise diagnosis and targeted treatment strategies.
What Does the Test Measure and Detect?
Our Amyloid Protein Identification Test employs a dual-methodology approach to ensure comprehensive analysis:
- Congo Red Stain Analysis: This classic histological stain confirms the presence of amyloid deposits by producing characteristic apple-green birefringence under polarized light microscopy
- LC-MS/MS Protein Identification: Advanced liquid chromatography-tandem mass spectrometry precisely identifies the specific amyloid protein subtype, including AL (light chain), AA (serum amyloid A), ATTR (transthyretin), and other rare variants
- Protein Characterization: Detailed analysis of amyloid protein composition and structural characteristics
- Tissue Localization: Identification of amyloid deposition patterns within specific organ systems
Who Should Consider This Test?
This advanced diagnostic test is recommended for individuals experiencing symptoms or clinical findings suggestive of amyloidosis:
- Patients with unexplained proteinuria, nephrotic syndrome, or renal impairment
- Individuals presenting with restrictive cardiomyopathy, arrhythmias, or heart failure without clear etiology
- Patients experiencing peripheral neuropathy, autonomic dysfunction, or carpal tunnel syndrome
- Those with hepatomegaly, splenomegaly, or gastrointestinal symptoms of unknown origin
- Individuals with macroglossia, periorbital purpura, or other characteristic physical findings
- Patients with monoclonal gammopathy or plasma cell dyscrasias
- Individuals with family history of hereditary amyloidosis
- Patients with chronic inflammatory conditions at risk for AA amyloidosis
Clinical Benefits of Amyloid Protein Identification
Early and accurate amyloid protein identification provides numerous clinical advantages:
- Precise Diagnosis: Differentiates between various amyloid subtypes, each requiring specific treatment approaches
- Treatment Guidance: Informs selection of appropriate therapies, including chemotherapy for AL amyloidosis, anti-inflammatory treatments for AA amyloidosis, or TTR stabilizers for hereditary forms
- Prognostic Information: Different amyloid subtypes have distinct clinical courses and outcomes
- Family Screening: Identifies hereditary forms requiring genetic counseling and family member evaluation
- Treatment Monitoring: Enables assessment of treatment response through serial testing
- Organ Transplantation Planning: Guides decisions regarding solid organ or stem cell transplantation
Understanding Your Test Results
Our comprehensive report provides detailed interpretation of your amyloid protein identification results:
- Positive for Amyloid: Confirmation of amyloid deposits with specific protein subtype identification
- AL Amyloidosis: Light chain-derived amyloid, typically associated with plasma cell disorders
- AA Amyloidosis: Serum amyloid A-derived, often secondary to chronic inflammatory conditions
- ATTR Amyloidosis: Transthyretin-derived, including both hereditary and wild-type forms
- Other Subtypes: Identification of rare amyloid proteins including Aβ2M, ApoAI, and others
- Negative Result: No amyloid deposits detected in the submitted tissue sample
Your healthcare provider will discuss the clinical implications of your specific results and develop an appropriate management plan based on the identified amyloid subtype and organ involvement.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Amyloid Protein Identification Test – Discount Price | $7,500 |
| Amyloid Protein Identification Test – Regular Price | $10,000 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Sample Requirements and Processing
For optimal testing accuracy, please ensure proper sample collection and submission:
- Sample Type: Formalin fixed paraffin embedded tissue block
- Shipping: Ship at room temperature with appropriate packaging
- Required Documentation: Copy of Histopathology report, biopsy site information, and complete clinical history
- Consent Form: Duly filled Test Send Out Consent Form (Form 35) is mandatory
- Turnaround Time: Samples received by the 7th of the month; comprehensive reports delivered within 2-3 weeks
Take Control of Your Health Today
Early diagnosis of amyloidosis can significantly impact treatment outcomes and quality of life. Our advanced Amyloid Protein Identification Test provides the definitive information needed for accurate diagnosis and appropriate treatment planning. Don’t wait while symptoms progress – take the first step toward clarity and effective management.
Call us now at +1(267) 388-9828 to schedule your test or speak with our specialist consultants. Our team is available to answer your questions and guide you through the testing process.
Alternatively, you can WhatsApp us at the same number for quick responses and convenient scheduling. Our dedicated patient coordinators will assist you with sample collection instructions, insurance inquiries, and appointment scheduling at your nearest testing facility.
Trust the experts in amyloidosis diagnostics. With years of specialized experience and state-of-the-art laboratory technology, we provide the accurate, timely results you need for informed healthcare decisions. Book your Amyloid Protein Identification Test today and take the crucial step toward definitive diagnosis and targeted treatment.

