AML Categorization PCR Test
Comprehensive Genetic Analysis for Acute Myeloid Leukemia
The AML Categorization PCR Test represents a breakthrough in molecular diagnostics for leukemia patients. This sophisticated genetic testing method provides critical insights into the specific genetic abnormalities driving Acute Myeloid Leukemia, enabling personalized treatment approaches and improved patient outcomes.
What is the AML Categorization PCR Test?
The AML Categorization PCR Test is a highly sensitive molecular diagnostic procedure that utilizes Real-Time Polymerase Chain Reaction (PCR) technology to detect specific genetic rearrangements associated with different subtypes of Acute Myeloid Leukemia. This advanced testing method amplifies and analyzes DNA sequences to identify chromosomal abnormalities that define various AML classifications.
What Does the Test Measure?
Our comprehensive AML Categorization PCR Test detects three critical genetic rearrangements:
- PML-RARA t(15;17)(q22;q12) Gene Rearrangement: Associated with acute promyelocytic leukemia (APL), this translocation creates a fusion gene that responds exceptionally well to targeted therapy with all-trans retinoic acid (ATRA).
- AML-ETO t(8;21) Gene Rearrangement: This common translocation in AML creates the RUNX1-RUNX1T1 fusion gene, typically associated with a favorable prognosis when treated with intensive chemotherapy.
- Inv(16)(p13q22)/t(16;16)(p13;q22) Gene Rearrangement: This inversion or translocation creates the CBFB-MYH11 fusion gene, often associated with core-binding factor AML and generally responsive to high-dose cytarabine therapy.
Who Should Consider This Test?
The AML Categorization PCR Test is recommended for individuals experiencing symptoms suggestive of acute leukemia or those with confirmed AML diagnosis requiring precise genetic classification:
- Patients presenting with unexplained fatigue, weakness, or persistent fever
- Individuals experiencing frequent infections or unusual bleeding/bruising
- Patients with abnormal complete blood count (CBC) results showing blasts or immature cells
- Individuals with newly diagnosed AML requiring genetic subtyping
- Patients undergoing treatment monitoring for known genetic AML subtypes
- Individuals with family history of hematologic malignancies
Key Benefits of AML Categorization Testing
Choosing the AML Categorization PCR Test provides numerous advantages for both patients and healthcare providers:
- Precise Diagnosis: Identifies specific genetic abnormalities that define AML subtypes
- Treatment Guidance: Helps oncologists select the most effective targeted therapies
- Prognostic Information: Provides valuable insights into disease progression and expected outcomes
- Minimal Residual Disease Monitoring: Enables sensitive detection of remaining leukemia cells after treatment
- Early Intervention: Facilitates timely treatment adjustments based on genetic findings
- Personalized Medicine: Supports development of individualized treatment plans
Understanding Your Test Results
Your AML Categorization PCR Test results will provide detailed information about the presence or absence of specific genetic rearrangements:
- Positive Result: Indicates detection of one or more genetic rearrangements, confirming the specific AML subtype and guiding targeted treatment approaches
- Negative Result: Suggests absence of the tested genetic abnormalities, which may indicate other AML subtypes requiring different diagnostic approaches
- Quantitative Results: Some tests provide quantitative measurements that help monitor treatment response and disease burden
Your oncologist will interpret these results in the context of your complete clinical picture, including bone marrow findings, blood counts, and other diagnostic information to develop the most appropriate treatment plan.
Test Pricing and Availability
| Test Name | Regular Price | Discount Price |
|---|---|---|
| AML Categorization PCR Test | $376 USD | $262 USD |
Test Specifications
- Turnaround Time: Sample collection Monday/Thursday by 11 AM; Results delivered Wednesday/Saturday
- Sample Type: 3 mL (2 mL minimum) whole blood or bone marrow from 1 Lavender Top (EDTA) tube
- Shipping Instructions: Ship refrigerated. DO NOT FREEZE
- Preparation: No special preparation required
Nationwide Availability
GGC DNA offers the AML Categorization PCR Test at our state-of-the-art facilities across the United States. We have convenient locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our certified laboratories maintain the highest standards of quality and accuracy.
Take Control of Your Health Today
Early and accurate genetic characterization of Acute Myeloid Leukemia can significantly impact treatment success and patient outcomes. Don’t wait to get the comprehensive genetic information you need for informed medical decisions.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your AML Categorization PCR Test appointment. Our genetic specialists are available to answer your questions and help you understand the testing process.
Book your test now and take the first step toward personalized leukemia management with cutting-edge molecular diagnostics from GGC DNA.
