ADRB2 Genotyping for Beta2 Agonist Responsiveness Test
Understanding ADRB2 Genetic Testing
The ADRB2 Genotyping for Beta2 Agonist Responsiveness Test represents a breakthrough in personalized medicine for respiratory conditions. This advanced pharmacogenomic analysis examines specific genetic variations in the beta-2 adrenergic receptor gene (ADRB2), which plays a critical role in how your body responds to commonly prescribed asthma medications known as beta2-agonists.
Genetic variations in the ADRB2 gene can significantly impact medication effectiveness, with certain polymorphisms leading to reduced bronchodilator response or increased risk of adverse effects. By understanding your unique genetic profile, healthcare providers can make more informed decisions about medication selection and dosing strategies.
What This Test Measures
Our comprehensive ADRB2 genotyping test analyzes specific single nucleotide polymorphisms (SNPs) within the ADRB2 gene that have been clinically validated to affect beta2-agonist responsiveness:
- Arg16Gly polymorphism (rs1042713)
- Gln27Glu polymorphism (rs1042714)
- Thr164Ile polymorphism (rs1800888)
These genetic variations influence receptor function, down-regulation patterns, and overall medication efficacy, providing crucial insights for treatment optimization.
Who Should Consider ADRB2 Genotyping?
This test is particularly valuable for individuals experiencing:
- Suboptimal response to standard beta2-agonist therapy
- Frequent asthma exacerbations despite medication use
- History of medication side effects or intolerance
- Poorly controlled asthma symptoms
- Need for frequent rescue inhaler use
- Planning long-term asthma management strategies
Clinical Indications Include:
- Patients with moderate to severe asthma
- Individuals requiring regular bronchodilator therapy
- Those with treatment-resistant respiratory symptoms
- Patients experiencing medication-related side effects
- Individuals considering long-acting beta2-agonist therapy
Benefits of ADRB2 Genetic Testing
Understanding your genetic profile offers numerous advantages for asthma management:
- Personalized Treatment Plans: Tailor medication selection based on your genetic predisposition
- Optimized Dosing Strategies: Adjust medication dosages for maximum effectiveness
- Reduced Side Effects: Minimize adverse reactions through genetic-guided prescribing
- Improved Symptom Control: Achieve better asthma control with genetically appropriate medications
- Enhanced Quality of Life: Experience fewer asthma exacerbations and hospital visits
- Cost-Effective Care: Avoid ineffective medications and associated healthcare costs
Understanding Your Test Results
Your ADRB2 genotyping results will provide detailed information about your genetic variations and their clinical implications:
Result Interpretation Guidelines:
- Favorable Genotype: Indicates optimal response to standard beta2-agonist therapy
- Intermediate Response: May require dosage adjustments or combination therapy
- Reduced Response: Suggests alternative medication classes may be more effective
- Increased Risk Profile: May indicate higher likelihood of adverse effects
All results include comprehensive interpretation by our molecular diagnostics specialists and clinical recommendations for your healthcare provider. It’s essential to discuss your results with your physician to develop the most appropriate treatment plan.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | ADRB2 Genotyping for Beta2 Agonist Responsiveness Test |
| Discount Price | $138 USD |
| Regular Price | $188 USD |
| Turnaround Time | Sample by 11 am; Report in 10 Working Days |
| Sample Type | 4 mL (2 mL min.) whole Blood in 1 Lavender top (EDTA) Tube |
| Shipping Instructions | Ship refrigerated. DO NOT FREEZE |
| Preparation | No Special preparation required |
| Testing Method | PCR Sequencing |
| Department | Molecular Diagnostics |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities nationwide. Our extensive network ensures accessible genetic testing services wherever you are located.
Take Control of Your Asthma Treatment
Don’t settle for trial-and-error medication approaches. Our ADRB2 genotyping test provides scientifically validated insights to optimize your asthma treatment strategy. With results available in just 10 working days and comprehensive clinical interpretation, you’ll receive the personalized guidance needed for effective respiratory care.
Ready to optimize your asthma treatment? Book your ADRB2 Genotyping test today by calling +1(267) 388-9828 or schedule your appointment online. Take the first step toward personalized respiratory care and improved quality of life.

