T-Cell Gene Rearrangement Mutation Detection Test
Comprehensive Introduction to T-Cell Gene Rearrangement Analysis
The T-Cell Gene Rearrangement Mutation Detection Test represents a cutting-edge molecular diagnostic approach that plays a pivotal role in modern oncology practice. This sophisticated test examines the unique genetic signatures created during T-cell development, providing clinicians with powerful tools to distinguish between normal immune responses and malignant T-cell proliferations. The importance of this test cannot be overstated, as it enables early and accurate diagnosis of T-cell malignancies, which are often challenging to identify through conventional methods alone.
What Does the Test Measure and Detect?
This advanced diagnostic test specifically targets and analyzes the genetic rearrangements that occur in T-cell receptor (TCR) genes during normal immune system development. The test detects:
- Clonal T-cell populations indicating malignancy
- Specific TCR gene rearrangements (TCR-beta, TCR-gamma)
- Monoclonal T-cell expansions characteristic of lymphomas
- Minimal residual disease following treatment
- T-cell lineage confirmation in ambiguous cases
Who Should Consider This Test?
This test is recommended for individuals experiencing symptoms or clinical findings suggestive of T-cell malignancies, including:
- Unexplained lymph node enlargement or swelling
- Persistent fever, night sweats, or unexplained weight loss
- Abnormal blood counts suggesting hematologic disorders
- Skin lesions or rashes that may indicate cutaneous T-cell lymphoma
- Patients with suspected T-cell leukemia or lymphoma
- Individuals requiring monitoring of known T-cell malignancies
- Cases where conventional pathology results are inconclusive
Key Benefits of T-Cell Gene Rearrangement Testing
Choosing this advanced diagnostic approach offers numerous advantages for patients and clinicians:
- Early Detection: Identifies T-cell malignancies at earlier stages when treatment is most effective
- Accurate Diagnosis: Provides definitive evidence of clonal T-cell populations
- Treatment Guidance: Helps oncologists develop targeted treatment strategies
- Disease Monitoring: Enables tracking of treatment response and disease progression
- Prognostic Information: Assists in predicting disease course and outcomes
- Minimal Sample Requirement: Requires only 4 mL of blood for comprehensive analysis
Understanding Your Test Results
Your T-Cell Gene Rearrangement Mutation Detection Test results will provide critical information about your immune system’s T-cell population:
Normal Results
A polyclonal pattern indicates a diverse T-cell population, which is characteristic of normal immune function and suggests the absence of malignant T-cell clones.
Abnormal Results
A monoclonal or oligoclonal pattern suggests the presence of a dominant T-cell clone, which may indicate:
- T-cell lymphoma or leukemia
- Other T-cell malignancies
- Reactive T-cell expansions in certain conditions
Clinical Interpretation
Your oncologist will interpret these results in the context of your clinical presentation, physical examination findings, and other diagnostic tests to provide a comprehensive assessment and treatment recommendation.
Test Pricing and Availability
| Test Name | Regular Price | Discount Price |
|---|---|---|
| T-Cell Gene Rearrangement Mutation Detection Test | $626 USD | $500 USD |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified collection centers ensures easy access to this vital diagnostic service.
Sample Collection and Processing
For optimal test accuracy, please note the following requirements:
- Sample Type: 4 mL (2 mL minimum) whole blood in 1 Lavender top (EDTA) tube
- Shipping: Ship refrigerated – DO NOT FREEZE
- Required Documentation: Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory
- Turnaround Time: 15 working days from sample receipt
Take Control of Your Health Today
Early and accurate diagnosis is crucial for successful treatment of T-cell malignancies. Our T-Cell Gene Rearrangement Mutation Detection Test provides the advanced molecular insights needed for informed medical decisions. With our discounted price of $500 USD and comprehensive nationwide coverage, accessing this sophisticated diagnostic tool has never been more convenient.
Ready to schedule your test? Contact our dedicated patient care team today at +1(267) 388-9828 or book your appointment online. Our experienced staff will guide you through the process and answer any questions you may have about this important diagnostic procedure.
