Multiplex Panel Cytogenetics PCR for 28 Translocations 80 Breakpoints CML AML ALL
Comprehensive Leukemia Genetic Analysis
The Multiplex Panel Cytogenetics PCR represents a cutting-edge molecular diagnostic approach specifically designed for comprehensive leukemia evaluation. This sophisticated testing methodology combines cytogenetic analysis with polymerase chain reaction (PCR) technology to simultaneously detect 28 critical chromosomal translocations and 80 genetic breakpoints associated with three major forms of leukemia: Chronic Myeloid Leukemia (CML), Acute Myeloid Leukemia (AML), and Acute Lymphoblastic Leukemia (ALL).
This advanced panel serves as an essential tool in modern hematologic oncology, providing clinicians with unprecedented insights into the genetic underpinnings of leukemia. By identifying specific chromosomal abnormalities and fusion genes, the test enables precise disease classification, accurate prognosis determination, and informed treatment selection. The multiplex approach significantly enhances diagnostic efficiency while maintaining exceptional sensitivity and specificity.
What This Test Detects and Measures
Comprehensive Genetic Marker Analysis
The Multiplex Panel Cytogenetics PCR test provides detailed analysis of:
- 28 Specific Chromosomal Translocations: Including BCR-ABL1 (Philadelphia chromosome), PML-RARA, RUNX1-RUNX1T1, and other critical fusion genes
- 80 Genetic Breakpoints: Comprehensive coverage of rearrangement sites across multiple chromosomes
- Leukemia Subtype Identification: Precise classification of CML, AML, and ALL subtypes
- Minimal Residual Disease Monitoring: Detection of low-level disease persistence after treatment
- Therapy Response Assessment: Quantitative measurement of genetic marker changes during treatment
Who Should Consider This Test
Clinical Indications and Symptoms
This comprehensive genetic panel is recommended for individuals experiencing:
- Unexplained fatigue, weakness, or persistent tiredness
- Frequent infections or unusual susceptibility to illness
- Unexplained bruising, bleeding, or petechiae
- Bone pain or tenderness, particularly in long bones
- Enlarged lymph nodes, spleen, or liver
- Night sweats, fever, or unintentional weight loss
- Abnormal complete blood count results
- Family history of hematologic malignancies
- Monitoring of known leukemia cases during treatment
Benefits of Comprehensive Leukemia Genetic Testing
Advantages for Patients and Clinicians
- Early and Accurate Diagnosis: Rapid identification of specific leukemia subtypes
- Personalized Treatment Planning: Targeted therapy selection based on genetic markers
- Prognostic Information: Better understanding of disease course and outcomes
- Treatment Monitoring: Objective assessment of therapy effectiveness
- Minimal Residual Disease Detection: Early identification of disease recurrence
- Comprehensive Genetic Profile: Single test covering multiple critical markers
- Time-Efficient Analysis: Simultaneous evaluation of multiple genetic abnormalities
Understanding Your Test Results
Interpretation Guidance
Your test results will provide detailed information about detected genetic abnormalities:
- Positive Results: Indicate the presence of specific chromosomal translocations or genetic breakpoints associated with leukemia subtypes
- Negative Results: Suggest absence of the tested genetic abnormalities, though other leukemia types may still be present
- Quantitative Measurements: For monitoring purposes, results may show the percentage of cells with specific genetic markers
- Clinical Correlation: Results should always be interpreted in conjunction with clinical findings and other laboratory tests
- Follow-up Recommendations: Your healthcare provider will discuss appropriate next steps based on your specific results
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | Multiplex Panel Cytogenetics PCR for 28 Translocations 80 Breakpoints CML AML ALL |
| Regular Price | $700 USD |
| Discount Price | $526 USD |
| Turnaround Time | 5-7 days |
| Sample Type | Bone marrow / Peripheral blood (Transport immediately) |
| Test Components | EDTA Vacutainer (3 ml) |
| Methodology | Multiplex PCR |
Pre-Test Instructions and Requirements
The Multiplex Panel Cytogenetics PCR test requires a Doctor’s prescription for most cases. Prescription requirements do not apply to surgery and pregnancy cases or individuals planning international travel. Please consult with your healthcare provider to determine if this test is appropriate for your specific clinical situation.
Nationwide Testing Availability
We maintain comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible, high-quality genetic testing services for patients throughout the country.
Book Your Comprehensive Leukemia Genetic Test Today
Take the first step toward comprehensive leukemia evaluation and personalized treatment planning. Our specialized genetic testing provides critical insights that can significantly impact your healthcare journey. Contact us today to schedule your Multiplex Panel Cytogenetics PCR test and benefit from our discounted pricing of $526 USD.
Call or WhatsApp: +1(267) 388-9828
Our genetic counseling team is available to answer your questions and help you understand the testing process. Early detection and precise genetic characterization can make a substantial difference in leukemia management and treatment outcomes.
