SDHD Gene Paraganglioma and Gastric Stromal Sarcoma NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Cancer Syndromes
The SDHD Gene Paraganglioma and Gastric Stromal Sarcoma NGS Genetic DNA Test represents a breakthrough in precision medicine for individuals at risk of inherited cancer conditions. This advanced diagnostic examination utilizes next-generation sequencing technology to analyze the SDHD (succinate dehydrogenase complex subunit D) gene, which plays a critical role in cellular energy production and tumor suppression.
What Does This Test Measure and Detect?
This sophisticated genetic analysis specifically targets the SDHD gene to identify pathogenic variants that predispose individuals to:
- Hereditary paraganglioma-pheochromocytoma syndrome (PGL1)
- Familial gastric stromal sarcoma
- Neuroendocrine tumors of the head and neck region
- Adrenal and extra-adrenal pheochromocytomas
- Gastrointestinal stromal tumors (GIST)
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing or with family history of:
- Multiple paragangliomas or pheochromocytomas
- Early-onset gastrointestinal stromal tumors
- Family members diagnosed with SDHD-related cancers
- Unexplained hypertension or cardiovascular symptoms
- Head and neck masses with endocrine characteristics
- Multiple endocrine neoplasia features
Clinical Benefits of SDHD Genetic Testing
Undergoing this comprehensive genetic assessment provides numerous advantages:
- Early Risk Identification: Detect genetic predisposition before symptom development
- Personalized Surveillance: Implement targeted screening protocols
- Family Planning Guidance: Make informed reproductive decisions
- Proactive Treatment Planning: Develop preventive strategies
- Family Member Screening: Identify at-risk relatives for early intervention
Understanding Your Test Results
Our genetic counseling team provides comprehensive result interpretation:
- Positive Result: Indicates presence of SDHD mutation requiring specialized monitoring
- Negative Result: No detected mutation, though family history remains important
- Variant of Uncertain Significance: Requires ongoing research and clinical correlation
- Personalized Management Plan: Tailored recommendations based on genetic findings
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with specialized centers in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to advanced genetic testing services regardless of your location.
Take Control of Your Genetic Health Today
Don’t wait to understand your genetic cancer risk profile. Our team of board-certified genetic counselors and oncology specialists are ready to guide you through the testing process and help interpret your results within the standard 3-4 week turnaround period.
Schedule your SDHD genetic testing consultation today by calling our dedicated genetics hotline at +1(267) 388-9828 or book your appointment online through our secure patient portal.
Sample collection is straightforward and can be performed using blood samples, extracted DNA, or a simple blood drop on FTA card. Prior to testing, we recommend genetic counseling to document your clinical history and create a comprehensive family pedigree chart for optimal result interpretation.
