LEFTY2 Gene Left-Right Axis Malformations NGS Genetic DNA Test
Comprehensive Genetic Testing for Organ Positioning Disorders
The LEFTY2 Gene Left-Right Axis Malformations NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for congenital disorders affecting organ positioning and development. This advanced test specifically targets the LEFTY2 gene, which plays a critical role in establishing the left-right body axis during embryonic development. Mutations in this gene can lead to serious congenital conditions that affect heart, lung, and abdominal organ positioning.
What Does This Test Measure?
This comprehensive genetic test utilizes Next-Generation Sequencing (NGS) technology to analyze the complete coding region of the LEFTY2 gene. The test detects:
- Point mutations and single nucleotide variants
- Small insertions and deletions
- Copy number variations affecting the LEFTY2 gene
- Pathogenic variants associated with left-right axis malformations
- Genetic markers for situs inversus and heterotaxy syndromes
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with:
- Family history of left-right axis malformations
- Congenital heart defects with abnormal organ positioning
- Situs inversus totalis or partial situs inversus
- Heterotaxy syndrome with complex cardiac anomalies
- Recurrent respiratory infections due to ciliary dysfunction
- Multiple congenital anomalies involving organ positioning
- Unexplained developmental delays with structural abnormalities
Clinical Benefits of LEFTY2 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous clinical advantages:
- Accurate Diagnosis: Confirms genetic basis for left-right axis disorders
- Personalized Treatment Planning: Guides surgical interventions and medical management
- Genetic Counseling: Provides recurrence risk information for family planning
- Early Intervention: Enables proactive management of associated complications
- Comprehensive Care Coordination: Facilitates multidisciplinary approach to treatment
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and medical geneticists. Results typically fall into three categories:
- Positive Result: Identifies a pathogenic variant in the LEFTY2 gene, confirming the genetic diagnosis and enabling targeted management strategies.
- Negative Result: No pathogenic variants detected, which may help rule out LEFTY2-related disorders or suggest alternative genetic causes.
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance is currently unknown, requiring further evaluation and possible family studies.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services for patients nationwide.
Take the Next Step Toward Genetic Clarity
If you or your loved one is experiencing symptoms or has a family history suggesting left-right axis malformations, don’t wait to get the answers you need. Our comprehensive LEFTY2 genetic test provides the clarity required for informed medical decisions and personalized care planning.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our genetic specialists are ready to guide you through the testing process and help you understand your results.
Remember to bring your clinical history and be prepared for a genetic counseling session where we’ll create a detailed pedigree chart of family members affected by similar conditions. This comprehensive approach ensures the most accurate interpretation of your genetic results and provides valuable insights for your entire family.
