ATP2A2 Gene Acrokeratosis Verruciformis NGS Genetic DNA Test
Comprehensive Genetic Testing for Inherited Skin Disorders
The ATP2A2 Gene Acrokeratosis Verruciformis NGS Genetic DNA Test represents a breakthrough in dermatological genetic diagnostics. This specialized test utilizes cutting-edge Next-Generation Sequencing (NGS) technology to analyze the ATP2A2 gene, which plays a critical role in calcium transport within skin cells. Mutations in this gene are directly linked to acrokeratosis verruciformis, a rare autosomal dominant skin condition characterized by distinctive wart-like lesions and other dermatological manifestations.
What Does This Test Measure and Detect?
This comprehensive genetic analysis specifically targets the ATP2A2 gene, which encodes the SERCA2 calcium pump protein essential for proper skin cell function. The test detects:
- Pathogenic variants and mutations in the ATP2A2 gene
- Single nucleotide polymorphisms (SNPs) associated with acrokeratosis verruciformis
- Deletion and duplication events affecting gene function
- Novel genetic variants with potential clinical significance
- Inheritance patterns for family genetic counseling
Who Should Consider This Genetic Test?
This test is recommended for individuals experiencing:
- Multiple flat-topped, wart-like papules on hands and feet
- Family history of acrokeratosis verruciformis or similar skin conditions
- Unexplained skin lesions that resemble warts but don’t respond to conventional treatments
- Co-occurrence of skin symptoms with other systemic manifestations
- Planning for pregnancy with family history of genetic skin disorders
- Diagnostic uncertainty regarding persistent dermatological conditions
Clinical Benefits of Genetic Testing
Undergoing the ATP2A2 genetic test provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out acrokeratosis verruciformis with high precision
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning Guidance: Provides essential information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates proactive management of potential complications
- Peace of Mind: Reduces diagnostic uncertainty and provides clarity about condition inheritance
- Research Contribution: Helps advance understanding of rare genetic skin disorders
Understanding Your Test Results
Your genetic test results will be thoroughly explained by our certified genetic counselors:
- Positive Result: Indicates the presence of a pathogenic ATP2A2 mutation, confirming acrokeratosis verruciformis diagnosis
- Negative Result: Suggests absence of known disease-causing variants in the ATP2A2 gene
- Variant of Uncertain Significance (VUS): Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines if you carry the genetic mutation without showing symptoms
Our genetic counseling team will provide comprehensive guidance on result interpretation, implications for family members, and recommendations for ongoing care and monitoring.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | ATP2A2 Gene Acrokeratosis Verruciformis NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Pre-test Requirements | Clinical History and Genetic Counseling Session |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about your skin condition or family genetic history cause unnecessary stress. Our comprehensive ATP2A2 genetic testing provides the answers you need for informed healthcare decisions. Our team of board-certified dermatologists and genetic specialists are ready to guide you through the testing process and help you understand your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your ATP2A2 Gene Acrokeratosis Verruciformis NGS Genetic DNA Test. Take control of your genetic health with confidence and clarity.
