WFS1 Gene Wolfram Syndrome Type 1 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Wolfram Syndrome
The WFS1 Gene Wolfram Syndrome Type 1 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying mutations in the WFS1 gene, which is responsible for Wolfram syndrome type 1. This rare autosomal recessive neurodegenerative disorder affects multiple body systems and typically manifests during childhood or adolescence. Our advanced Next-Generation Sequencing technology provides unparalleled accuracy in detecting pathogenic variants, enabling healthcare providers to make informed clinical decisions and develop targeted management strategies.
What Does This Test Measure?
This comprehensive genetic test specifically analyzes the WFS1 (Wolframin ER Transmembrane Glycoprotein) gene for mutations associated with Wolfram syndrome type 1. The test detects:
- Point mutations, insertions, and deletions in the WFS1 gene
- Pathogenic variants affecting wolframin protein function
- Autosomal recessive inheritance patterns
- Genetic markers for diabetes insipidus and optic atrophy
- Neurological and endocrine system involvement indicators
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with symptoms suggestive of Wolfram syndrome, including:
- Children or adolescents with unexplained diabetes mellitus
- Patients experiencing progressive vision loss due to optic atrophy
- Individuals with diabetes insipidus (excessive thirst and urination)
- Those with sensorineural hearing loss developing in childhood
- Patients with neurological symptoms including ataxia or seizures
- Individuals with a family history of Wolfram syndrome
- Unexplained endocrine abnormalities in young patients
Key Benefits of WFS1 Genetic Testing
Undergoing the WFS1 Gene Wolfram Syndrome Type 1 NGS Genetic DNA Test provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out Wolfram syndrome with high precision
- Early Intervention: Enables proactive management of symptoms before severe complications develop
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Personalized Treatment: Guides targeted therapeutic approaches based on genetic findings
- Prognostic Information: Helps predict disease progression and potential complications
- Differential Diagnosis: Distinguishes Wolfram syndrome from other similar conditions
Understanding Your Test Results
Our comprehensive genetic counseling support helps you interpret your WFS1 gene test results:
- Positive Result: Indicates the presence of pathogenic WFS1 mutations consistent with Wolfram syndrome diagnosis
- Negative Result: Suggests no detectable mutations, though clinical correlation remains essential
- Variant of Uncertain Significance: Requires additional family studies and clinical evaluation
- Carrier Status: Identifies individuals with single mutation who may pass the condition to offspring
All results are accompanied by detailed explanations and recommendations from our certified genetic counselors.
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Control of Your Genetic Health Today
Don’t let uncertainty about Wolfram syndrome affect your quality of life. Our state-of-the-art WFS1 genetic testing provides the clarity you need for proper diagnosis and management. With results available in 3-4 weeks and comprehensive genetic counseling included, you’ll receive the expert guidance necessary to understand your results and make informed healthcare decisions.
Ready to schedule your WFS1 Gene Wolfram Syndrome Type 1 NGS Genetic DNA Test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and help you take the next step toward genetic clarity and improved health outcomes.
