NME8 Gene Primary Ciliary Dyskinesia Type 6 NGS Genetic DNA Test
Comprehensive Genetic Testing for Respiratory and Fertility Disorders
The NME8 Gene Primary Ciliary Dyskinesia Type 6 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations responsible for Primary Ciliary Dyskinesia (PCD) Type 6. This specialized test provides crucial insights into the genetic basis of ciliary dysfunction, enabling early intervention and personalized treatment strategies for affected individuals and families.
What is Primary Ciliary Dyskinesia Type 6?
Primary Ciliary Dyskinesia Type 6 is a rare genetic disorder characterized by impaired ciliary function throughout the body. Cilia are microscopic, hair-like structures that line the respiratory tract, reproductive system, and other organs. When these cilia don’t function properly due to NME8 gene mutations, individuals experience chronic respiratory infections, sinusitis, and potential fertility challenges.
What the Test Measures and Detects
This advanced genetic test specifically targets the NME8 gene using Next-Generation Sequencing (NGS) technology to identify:
- Point mutations and small insertions/deletions in the NME8 gene
- Genetic variations affecting ciliary structure and function
- Inheritance patterns for family planning decisions
- Specific mutations associated with PCD Type 6 severity
Advanced NGS Technology
Our Next-Generation Sequencing approach provides comprehensive coverage of the NME8 gene with exceptional accuracy and sensitivity. This technology enables simultaneous analysis of multiple genetic regions, ensuring thorough detection of even rare mutations that might be missed by conventional testing methods.
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Chronic Respiratory Symptoms: Persistent cough, wheezing, or recurrent pneumonia from early childhood
- Recurrent Sinus and Ear Infections: Frequent sinusitis, middle ear infections, or hearing loss
- Unexplained Infertility: Especially in males with suspected sperm motility issues
- Family History: Individuals with family members diagnosed with PCD or similar respiratory conditions
- Neonatal Respiratory Distress: Babies experiencing breathing difficulties shortly after birth
- Situs Inversus: Individuals with organs positioned on the opposite side of the body
Clinical Indications
Healthcare providers typically recommend this test when patients present with characteristic PCD symptoms that haven’t responded to conventional treatments, or when there’s a strong family history suggesting genetic predisposition to ciliary disorders.
Benefits of Taking the NME8 Genetic Test
- Early Diagnosis: Identify genetic causes before severe complications develop
- Personalized Treatment: Develop targeted management strategies based on genetic findings
- Family Planning: Make informed reproductive decisions with genetic counseling
- Improved Quality of Life: Implement preventive measures to reduce infection frequency
- Comprehensive Care: Coordinate with ENT specialists and genetic counselors for holistic management
- Peace of Mind: Resolve diagnostic uncertainty and establish clear treatment pathways
Long-term Health Management
Early genetic diagnosis enables proactive management of PCD Type 6, potentially preventing irreversible lung damage and improving overall respiratory health throughout the patient’s lifetime.
Understanding Your Test Results
Your genetic test results will fall into one of several categories, each with specific implications for your health management:
- Positive Result: Confirms the presence of NME8 gene mutations associated with PCD Type 6, enabling targeted treatment and monitoring
- Negative Result: Suggests that NME8 gene mutations are not the cause of symptoms, potentially indicating other genetic or environmental factors
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Determines if you carry one copy of a mutated gene, important for family planning decisions
Genetic Counseling Support
All positive results include comprehensive genetic counseling to help you understand the implications for your health and family. Our certified genetic counselors provide personalized guidance on treatment options, lifestyle modifications, and family planning considerations.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | NME8 Gene Primary Ciliary Dyskinesia Type 6 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) |
| Specialty | ENT Doctor, Genetics |
Pre-Test Requirements
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to discuss testing implications
- Family pedigree analysis for inheritance pattern assessment
- Discussion of potential outcomes and their implications
Nationwide Testing Availability
GGC DNA provides comprehensive genetic testing services across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing for patients nationwide.
Convenient Sample Collection
We offer multiple sample collection options to accommodate your preferences and location. Choose from blood draws at our certified centers, DNA extraction services, or convenient FTA card collection for simplified testing.
Take Control of Your Genetic Health Today
Don’t let uncertainty about genetic conditions affect your quality of life. The NME8 Gene Primary Ciliary Dyskinesia Type 6 NGS Genetic DNA Test provides definitive answers and clear pathways for managing your health. Our team of genetic specialists, ENT doctors, and certified counselors are ready to support you through every step of the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic health.
Early genetic testing can make a significant difference in managing Primary Ciliary Dyskinesia Type 6 and improving long-term health outcomes. Contact us now to book your test and receive professional genetic counseling support.
