CLDN14 Gene Deafness Autosomal Recessive Type 29 NGS Genetic DNA Test
Comprehensive Genetic Screening for Hereditary Hearing Loss
The CLDN14 Gene Deafness Autosomal Recessive Type 29 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing disorders. This advanced screening utilizes cutting-edge Next-Generation Sequencing (NGS) technology to identify specific mutations in the CLDN14 gene that are responsible for autosomal recessive nonsyndromic hearing loss type 29. Understanding your genetic predisposition to hearing impairment can provide invaluable insights for early intervention and personalized management strategies.
What Does This Test Measure and Detect?
This comprehensive genetic test specifically targets the CLDN14 gene, which encodes claudin-14, a crucial protein component of tight junctions in the inner ear. The test detects:
- Pathogenic variants and mutations in the CLDN14 gene
- Single nucleotide polymorphisms (SNPs) associated with hearing loss
- Deletions, insertions, and other structural variations
- Autosomal recessive inheritance patterns
- Genetic markers for congenital or early-onset deafness
CLDN14 mutations disrupt the formation of tight junctions in the cochlea, compromising the endocochlear potential essential for proper hearing function. Our NGS technology provides comprehensive coverage of the entire CLDN14 gene with exceptional accuracy and sensitivity.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals and families experiencing:
- Family history of hereditary hearing loss or deafness
- Congenital hearing impairment in infants and children
- Progressive hearing loss beginning in early childhood
- Unexplained sensorineural hearing loss
- Couples planning pregnancy with family history of deafness
- Individuals from populations with higher incidence of CLDN14 mutations
- Newborns failing routine hearing screenings
Key Benefits of CLDN14 Genetic Testing
Undergoing this genetic screening provides numerous advantages for patients and families:
- Early Diagnosis: Enables early detection of genetic hearing loss before significant impairment occurs
- Personalized Management: Guides appropriate hearing intervention strategies and treatment plans
- Reproductive Planning: Provides crucial information for family planning and genetic counseling
- Prognostic Information: Helps predict the progression and severity of hearing loss
- Peace of Mind: Reduces uncertainty and anxiety about hereditary conditions
- Comprehensive Analysis: NGS technology ensures thorough examination of the CLDN14 gene
Understanding Your Test Results
Our genetic counselors provide comprehensive interpretation of your CLDN14 test results:
- Positive Result: Indicates the presence of pathogenic CLDN14 mutations. This confirms the genetic basis of hearing loss and enables targeted management strategies.
- Negative Result: Suggests that CLDN14 mutations are not responsible for the hearing concerns, directing further investigation to other potential causes.
- Variant of Uncertain Significance: Some genetic changes may require additional family studies or research to determine clinical significance.
- Carrier Status: Identifies individuals who carry one copy of a mutated gene but typically do not show symptoms.
All results are accompanied by detailed genetic counseling to ensure complete understanding and appropriate next steps.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | CLDN14 Gene Deafness Autosomal Recessive Type 29 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | ENT Doctor, Genetics Department |
Nationwide Accessibility and Convenience
We have branches across the United States, making genetic testing accessible to patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and healthcare professionals ensures you receive comprehensive support throughout the testing process.
Take Control of Your Genetic Health Today
Don’t let uncertainty about hereditary hearing loss affect your quality of life. The CLDN14 Gene Deafness Autosomal Recessive Type 29 NGS Genetic DNA Test provides the clarity and information needed to make informed healthcare decisions. Early detection through genetic testing can significantly improve outcomes and quality of life for individuals with hereditary hearing conditions.
Book your genetic screening appointment today by calling +1(267) 388-9828 or visiting our nearest branch. Our genetic specialists are ready to guide you through the testing process and help you understand your results.
Take the first step toward understanding your genetic predisposition to hearing loss and ensure the best possible hearing health for you and your family.
