TMC1 Gene Deafness Autosomal Dominant Type 36 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Hearing Loss
The TMC1 Gene Deafness Autosomal Dominant Type 36 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing disorders. This advanced screening utilizes cutting-edge Next-Generation Sequencing (NGS) technology to identify mutations in the TMC1 gene, which plays a critical role in auditory function and hair cell development within the inner ear.
What Does This Test Measure?
This comprehensive genetic analysis specifically targets the TMC1 gene, detecting mutations associated with Autosomal Dominant Deafness Type 36 (DFNA36). The test examines:
- Point mutations and single nucleotide variants in the TMC1 gene
- Small insertions and deletions affecting gene function
- Genetic variations that disrupt hair cell mechanotransduction
- Mutations causing progressive sensorineural hearing loss
Who Should Consider This Test?
This genetic screening is recommended for individuals experiencing:
- Progressive hearing loss beginning in childhood or early adulthood
- Family history of hereditary hearing impairment
- Unexplained sensorineural hearing loss without environmental causes
- Patients with suspected genetic hearing disorders
- Individuals planning family with known TMC1 gene mutations
Key Benefits of TMC1 Genetic Testing
- Early Detection: Identify genetic predisposition before significant hearing loss occurs
- Personalized Management: Develop targeted hearing conservation strategies
- Family Planning: Make informed decisions about genetic inheritance risks
- Treatment Guidance: Optimize hearing aid and cochlear implant timing
- Peace of Mind: Understand the genetic basis of hearing concerns
Understanding Your Test Results
Your genetic test results will fall into one of several categories:
- Positive Result: Indicates the presence of a known pathogenic TMC1 mutation, confirming genetic hearing loss predisposition
- Negative Result: No known disease-causing mutations detected, though other genetic or environmental factors may still contribute to hearing issues
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact, requiring ongoing monitoring
- Carrier Status: Important for family planning and understanding inheritance patterns
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | TMC1 Gene Deafness Autosomal Dominant Type 36 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your TMC1 genetic test, we recommend:
- Complete clinical history documentation
- Genetic counseling session to discuss implications and expectations
- Family pedigree analysis to identify inheritance patterns
- Consultation with an ENT specialist for comprehensive hearing evaluation
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services for patients nationwide.
Take Control of Your Hearing Health
Don’t let uncertainty about hereditary hearing loss affect your quality of life. The TMC1 Gene Deafness Autosomal Dominant Type 36 NGS Genetic DNA Test provides the clarity needed for proactive hearing health management. Our experienced genetic counselors and ENT specialists are available to guide you through the testing process and results interpretation.
Ready to schedule your genetic test? Contact us today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic hearing health with our comprehensive TMC1 genetic analysis.
