SLC17A8 Gene Deafness Autosomal Dominant Type 25 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Hearing Loss
The SLC17A8 Gene Deafness Autosomal Dominant Type 25 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing disorders. This advanced test specifically targets mutations in the SLC17A8 gene, which encodes a vesicular glutamate transporter crucial for proper auditory function. When this gene malfunctions, it disrupts glutamate signaling in the inner ear, leading to progressive sensorineural hearing loss that typically begins in childhood or early adulthood.
What This Test Measures and Detects
Our NGS-based genetic test provides comprehensive analysis of the SLC17A8 gene to identify:
- Point mutations and single nucleotide variants affecting gene function
- Insertions and deletions that disrupt protein structure
- Copy number variations impacting gene dosage
- Splice site mutations affecting RNA processing
- Regulatory region variants influencing gene expression
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Progressive hearing loss beginning in childhood or early adulthood
- Family history of autosomal dominant hearing impairment
- Unexplained sensorineural hearing loss without environmental causes
- Planning pregnancy with known family history of genetic hearing disorders
- Children showing delayed speech development due to hearing issues
- Individuals with normal hearing but family members affected by DFNA25
Clinical Benefits of Genetic Testing
Early genetic diagnosis through our SLC17A8 test provides numerous advantages:
- Accurate Diagnosis: Confirms genetic cause of hearing loss, eliminating diagnostic uncertainty
- Family Planning Guidance: Enables informed reproductive decisions and genetic counseling
- Personalized Management: Guides appropriate hearing aid selection and communication strategies
- Proactive Monitoring: Allows for early intervention and hearing preservation efforts
- Genetic Counseling: Provides risk assessment for family members and future generations
Understanding Your Test Results
Our comprehensive genetic report includes detailed interpretation of your results:
- Positive Result: Indicates presence of pathogenic SLC17A8 mutation, confirming DFNA25 diagnosis
- Negative Result: Suggests hearing loss may have other genetic or environmental causes
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Important for family planning and genetic counseling purposes
All results are accompanied by detailed explanations and recommendations for next steps, including referral to ENT specialists and genetic counselors.
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | SLC17A8 Gene Deafness Autosomal Dominant Type 25 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Accessibility
We have diagnostic centers conveniently located across major metropolitan areas throughout the United States, including New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards regardless of location.
Pre-Test Preparation Requirements
Before scheduling your test, please ensure you have:
- Complete clinical history documenting hearing loss progression and symptoms
- Family pedigree chart showing affected relatives and inheritance patterns
- Previous audiological evaluations and hearing test results
- Genetic counseling session to discuss testing implications and expectations
Take Control of Your Hearing Health Today
Don’t let genetic hearing loss remain a mystery. Our SLC17A8 genetic test provides the clarity needed for proper diagnosis and management. With our discounted price of $500 USD and comprehensive nationwide coverage, advanced genetic testing has never been more accessible.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or speak with our genetic counseling team. Early detection can make a significant difference in managing hereditary hearing conditions and planning for the future.
