MEFV Gene Mediterranean Fever NGS Genetic DNA Test
Comprehensive Genetic Testing for Familial Mediterranean Fever
The MEFV Gene Mediterranean Fever NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying familial Mediterranean fever (FMF), an inherited autoinflammatory disorder characterized by recurrent episodes of fever and inflammation. This advanced genetic test utilizes next-generation sequencing technology to provide comprehensive analysis of the MEFV gene, enabling accurate diagnosis and personalized treatment strategies for patients suffering from this complex condition.
What Does the MEFV Gene Test Measure?
This sophisticated genetic test specifically targets the MEFV (Mediterranean Fever) gene located on chromosome 16p13.3. The test detects:
- Pathogenic mutations associated with familial Mediterranean fever
- Common MEFV gene variants including M694V, V726A, M680I, and M694I
- Rare and novel genetic alterations affecting pyrin protein function
- Autosomal recessive inheritance patterns characteristic of FMF
Who Should Consider This Genetic Test?
Individuals experiencing the following symptoms should consider the MEFV Gene Mediterranean Fever NGS Genetic DNA Test:
- Recurrent unexplained fevers lasting 1-3 days
- Severe abdominal pain mimicking acute abdomen
- Chest pain due to pleuritis or pericarditis
- Joint inflammation and arthritis
- Erysipelas-like skin lesions
- Family history of Mediterranean fever or similar symptoms
- Ethnic background including Mediterranean, Middle Eastern, or Jewish ancestry
Key Benefits of MEFV Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Definitive Diagnosis: Confirms or rules out familial Mediterranean fever with high accuracy
- Personalized Treatment: Guides appropriate colchicine therapy and management
- Family Planning: Provides genetic counseling for inheritance risk assessment
- Symptom Management: Helps prevent amyloidosis complications through early intervention
- Differential Diagnosis: Distinguishes FMF from other periodic fever syndromes
Understanding Your Test Results
Our genetic specialists provide comprehensive interpretation of your MEFV gene analysis:
- Positive Result: Indicates pathogenic mutations confirming FMF diagnosis
- Negative Result: Suggests low probability of FMF, though clinical correlation is essential
- Variant of Uncertain Significance: Requires additional clinical evaluation and family studies
- Carrier Status: Identifies individuals with single mutation who may pass the condition to offspring
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | MEFV Gene Mediterranean Fever NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Methodology | Next-Generation Sequencing (NGS) Technology |
| Specialty | General Physician, Genetics |
Pre-Test Requirements
Before undergoing the MEFV Gene Mediterranean Fever NGS Genetic DNA Test, patients should:
- Provide complete clinical history including fever patterns and associated symptoms
- Participate in genetic counseling session to create detailed family pedigree
- Discuss testing implications with healthcare provider
- Understand potential outcomes and their clinical significance
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and healthcare professionals ensures accessible, high-quality genetic testing services nationwide.
Take Control of Your Health Today
Don’t let unexplained recurrent fevers and inflammatory symptoms disrupt your life. The MEFV Gene Mediterranean Fever NGS Genetic DNA Test provides the clarity needed for proper diagnosis and effective management of familial Mediterranean fever. Our team of genetic specialists is ready to guide you through the testing process and help you understand your results.
Book your MEFV Gene Mediterranean Fever NGS Genetic DNA Test today by calling +1(267) 388-9828 or schedule your appointment online. Take the first step toward accurate diagnosis and personalized treatment for recurrent fever syndromes.
