PPARG Gene Lipodystrophy Familial Partial Type 3 NGS Genetic DNA Test
Comprehensive Genetic Testing for Familial Partial Lipodystrophy
The PPARG Gene Lipodystrophy Familial Partial Type 3 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for metabolic disorders. This advanced test specifically targets mutations in the peroxisome proliferator-activated receptor gamma (PPARG) gene, which plays a critical role in adipocyte differentiation, lipid metabolism, and insulin sensitivity. When this gene malfunctions, it leads to familial partial lipodystrophy type 3 – a rare genetic condition characterized by abnormal fat distribution and severe metabolic complications.
What This Test Measures and Detects
Our state-of-the-art NGS (Next-Generation Sequencing) technology comprehensively analyzes the entire PPARG gene to identify:
- Point mutations and single nucleotide variants
- Insertions and deletions affecting gene function
- Missense, nonsense, and frameshift mutations
- Regulatory region abnormalities
- Known pathogenic variants associated with lipodystrophy
The test provides precise genetic information that helps confirm diagnosis, assess disease severity, and guide appropriate therapeutic interventions.
Who Should Consider This Genetic Test
This test is particularly recommended for individuals presenting with:
- Progressive fat loss from arms, legs, and buttocks
- Accumulation of fat in the face, neck, and abdominal region
- Severe insulin resistance or type 2 diabetes at young age
- Elevated triglyceride levels and low HDL cholesterol
- Fatty liver disease (hepatic steatosis)
- Family history of similar metabolic abnormalities
- Women with polycystic ovary syndrome and metabolic issues
- Unexplained acanthosis nigricans (darkened skin patches)
Significant Benefits of Genetic Testing
Undergoing PPARG gene testing provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms familial partial lipodystrophy type 3 with genetic evidence
- Personalized Treatment: Enables targeted therapies including PPARγ agonists
- Family Planning: Provides information for genetic counseling and reproductive decisions
- Early Intervention: Allows proactive management of metabolic complications
- Disease Monitoring: Establishes baseline for tracking disease progression
- Research Contribution: Advances understanding of rare metabolic disorders
Understanding Your Test Results
Our comprehensive genetic report includes detailed interpretation of your results:
- Positive Result: Identifies a pathogenic mutation in the PPARG gene, confirming familial partial lipodystrophy type 3 diagnosis
- Negative Result: No mutation detected, suggesting other causes for symptoms should be investigated
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Information about inheritance patterns and family member risks
All results are accompanied by detailed explanations and recommendations for next steps, including consultation with metabolic specialists and genetic counselors.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures accessible genetic testing services regardless of your location.
Pre-Test Requirements
To ensure optimal testing outcomes, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential results and their impact
Take Control of Your Metabolic Health Today
Don’t let unexplained metabolic symptoms affect your quality of life. Our PPARG Gene Lipodystrophy Familial Partial Type 3 NGS Genetic DNA Test provides the clarity needed for proper diagnosis and management. With our discounted price of $500 (regularly $700), this comprehensive genetic analysis is both accessible and invaluable for your health journey.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your metabolic health.
Our team of genetic specialists and metabolic disorder experts is ready to guide you through the testing process, answer your questions, and provide the support you need for informed healthcare decisions.
