LMNA Gene Lipodystrophy Type 2 Familial Partial NGS Genetic DNA Test
Understanding LMNA Gene Lipodystrophy Type 2
Familial partial lipodystrophy type 2 (FPLD2) is a rare inherited metabolic disorder characterized by abnormal fat distribution throughout the body. This condition results from mutations in the LMNA gene, which provides instructions for producing lamin A and lamin C proteins essential for maintaining nuclear structure and function. Our advanced NGS Genetic DNA Test offers comprehensive analysis of the LMNA gene to identify pathogenic variants responsible for this complex metabolic syndrome.
What Does This Test Measure?
This sophisticated genetic test utilizes next-generation sequencing technology to examine the entire LMNA gene for mutations associated with familial partial lipodystrophy type 2. The test specifically detects:
- Point mutations affecting lamin A/C protein structure
- Small insertions and deletions within the LMNA gene
- Genetic variants known to cause abnormal fat distribution patterns
- Mutations linked to insulin resistance and metabolic complications
- Inherited genetic changes passed through family generations
Who Should Consider This Genetic Test?
This test is particularly important for individuals displaying symptoms suggestive of familial partial lipodystrophy type 2, including:
- Progressive loss of subcutaneous fat from arms, legs, and buttocks
- Accumulation of fat in the face, neck, and abdominal region
- Severe insulin resistance developing in adolescence or early adulthood
- Early-onset type 2 diabetes despite normal body weight
- Hypertriglyceridemia and abnormal lipid profiles
- Family history of similar fat distribution patterns
- Women with polycystic ovary syndrome and metabolic abnormalities
- Individuals with acanthosis nigricans and metabolic syndrome features
Clinical Benefits of Genetic Testing
Undergoing LMNA gene testing provides numerous clinical advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms or rules out familial partial lipodystrophy type 2 with high precision
- Personalized Treatment: Enables targeted management strategies for metabolic complications
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates proactive management to prevent diabetes and cardiovascular complications
- Disease Monitoring: Establishes baseline for tracking disease progression and treatment response
Understanding Your Test Results
Our comprehensive genetic analysis provides clear, actionable results with detailed interpretation:
- Positive Result: Indicates the presence of a pathogenic LMNA gene mutation associated with familial partial lipodystrophy type 2. This confirms the diagnosis and enables targeted management approaches.
- Negative Result: Suggests no detectable LMNA mutation, though clinical correlation remains essential as other genetic or acquired forms of lipodystrophy may be present.
- Variant of Uncertain Significance: Some genetic changes may require additional family studies or functional analysis to determine clinical significance.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | LMNA Gene Lipodystrophy Type 2 Familial Partial NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and Philadelphia. Our certified genetic counselors and medical professionals ensure you receive personalized care and accurate results.
Take Control of Your Genetic Health Today
Don’t let uncertainty about your metabolic health continue. Our LMNA Gene Lipodystrophy Type 2 test provides the clarity needed for proper diagnosis and management. Early detection through genetic testing can significantly improve long-term health outcomes and quality of life.
Book your genetic test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Our genetic specialists are available to discuss your testing options and answer any questions about familial partial lipodystrophy type 2.
