GNA11 Gene Hypocalcemia Autosomal Dominant 2 NGS Genetic DNA Test
Comprehensive Genetic Testing for Calcium Regulation Disorders
The GNA11 Gene Hypocalcemia Autosomal Dominant 2 NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for metabolic disorders. This advanced genetic test specifically targets mutations in the GNA11 gene, which plays a crucial role in calcium-sensing receptor signaling and maintaining proper calcium homeostasis in the body. Autosomal dominant hypocalcemia type 2 is a rare inherited condition characterized by low blood calcium levels that can lead to serious neurological and muscular complications if left undiagnosed.
What Does This Test Measure and Detect?
Our comprehensive NGS-based genetic analysis examines the entire coding region of the GNA11 gene to identify pathogenic variants responsible for autosomal dominant hypocalcemia type 2. The test specifically detects:
- Missense mutations affecting calcium-sensing receptor function
- Frameshift mutations disrupting protein structure
- Nonsense mutations leading to truncated proteins
- Splice site variants affecting gene expression
- Copy number variations within the GNA11 locus
Using state-of-the-art Next-Generation Sequencing technology, we achieve exceptional accuracy in variant detection, providing clinicians with reliable genetic information for diagnosis and treatment planning.
Who Should Consider This Genetic Test?
This specialized genetic test is recommended for individuals presenting with:
- Unexplained persistent hypocalcemia (low blood calcium)
- Neuromuscular symptoms including muscle cramps, spasms, or tetany
- Family history of hypocalcemia or calcium metabolism disorders
- Seizures or neurological symptoms without clear etiology
- Developmental delays in children with calcium abnormalities
- Abnormal electrocardiogram findings related to electrolyte imbalances
- Previous inconclusive calcium metabolism evaluations
Clinical Benefits of Genetic Testing
Undergoing the GNA11 Gene Hypocalcemia Autosomal Dominant 2 test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms genetic etiology of hypocalcemia symptoms
- Personalized Treatment: Enables targeted calcium and vitamin D therapy
- Family Planning: Provides genetic counseling information for family members
- Early Intervention: Facilitates proactive management to prevent complications
- Differential Diagnosis: Distinguishes between different forms of hypocalcemia
- Long-term Monitoring: Establishes baseline for ongoing calcium management
Understanding Your Test Results
Our comprehensive genetic report provides clear interpretation of your results:
- Positive Result: Indicates presence of pathogenic GNA11 mutation confirming autosomal dominant hypocalcemia type 2 diagnosis
- Negative Result: Suggests absence of detectable GNA11 mutations, though other genetic causes should be considered
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation
- Carrier Status: Determines inheritance patterns for family counseling
All results are accompanied by detailed clinical guidance and recommendations for follow-up care with your healthcare provider.
Test Pricing and Sample Requirements
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States with convenient locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Pre-Test Requirements and Genetic Counseling
Before undergoing testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to discuss implications
- Family pedigree chart development
- Informed consent process completion
- Discussion of potential outcomes and management options
Take Control of Your Genetic Health Today
Don’t let unexplained hypocalcemia symptoms affect your quality of life. Our advanced GNA11 genetic testing provides the answers you need for proper diagnosis and targeted treatment. With our discounted price of $500 and comprehensive nationwide coverage, accessing cutting-edge genetic testing has never been more convenient.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your calcium metabolism health.
