PPP1R17 Gene Hypercholesterolemia Susceptibility NGS Genetic DNA Test
Comprehensive Genetic Assessment for Cholesterol Management
The PPP1R17 Gene Hypercholesterolemia Susceptibility NGS Genetic DNA Test represents a breakthrough in personalized cardiovascular medicine, offering individuals unprecedented insight into their genetic predisposition to elevated cholesterol levels. This advanced diagnostic tool utilizes cutting-edge Next-Generation Sequencing technology to analyze the PPP1R17 gene, which plays a crucial role in cholesterol metabolism and regulation.
Understanding Hypercholesterolemia and Genetic Susceptibility
Hypercholesterolemia, characterized by abnormally high levels of cholesterol in the blood, significantly increases the risk of cardiovascular diseases, including heart attacks and strokes. While lifestyle factors contribute to cholesterol levels, genetic predisposition accounts for approximately 40-60% of the variation in cholesterol concentrations among individuals. The PPP1R17 gene encodes a regulatory subunit that influences cholesterol homeostasis, and specific variations in this gene can predispose individuals to developing hypercholesterolemia.
What This Advanced Test Measures and Detects
Our comprehensive NGS-based analysis examines the complete coding region of the PPP1R17 gene, identifying:
- Single nucleotide polymorphisms (SNPs) associated with cholesterol metabolism
- Copy number variations affecting gene function
- Rare genetic variants with significant clinical implications
- Specific mutations linked to increased hypercholesterolemia susceptibility
- Genetic markers that influence response to cholesterol-lowering medications
Clinical Significance of PPP1R17 Gene Analysis
The PPP1R17 gene product interacts with protein phosphatase 1, playing a regulatory role in various cellular processes including lipid metabolism. Genetic variations in this gene can disrupt normal cholesterol regulation, leading to persistent elevation of LDL cholesterol levels even in individuals following healthy lifestyles.
Who Should Consider This Genetic Test?
This advanced genetic assessment is particularly recommended for individuals experiencing:
- Unexplained elevated cholesterol levels despite healthy lifestyle
- Family history of early-onset cardiovascular disease (before age 55 in men, 65 in women)
- Multiple family members with hypercholesterolemia
- Resistance to standard cholesterol-lowering medications
- Personal history of premature coronary artery disease
- Children or young adults with significantly elevated cholesterol
- Individuals with xanthomas (cholesterol deposits in skin or tendons)
Early Detection for Proactive Health Management
Identifying genetic susceptibility to hypercholesterolemia enables healthcare providers to implement targeted prevention strategies years before clinical symptoms manifest, potentially preventing serious cardiovascular complications.
Comprehensive Benefits of Genetic Testing
Undergoing the PPP1R17 Gene Hypercholesterolemia Susceptibility Test provides numerous advantages:
- Personalized Risk Assessment: Understand your specific genetic predisposition to cholesterol issues
- Early Intervention Opportunities: Implement preventive measures before significant health problems develop
- Targeted Treatment Planning: Guide medication selection based on genetic profile
- Family Health Awareness: Provide valuable information for relatives who may share similar genetic risks
- Lifestyle Optimization: Tailor diet and exercise recommendations to your genetic makeup
- Peace of Mind: Reduce uncertainty about cholesterol management
- Cost-Effective Prevention: Potentially avoid expensive future medical treatments through early detection
Understanding Your Test Results
Our comprehensive genetic report provides clear, actionable information:
Positive Result Interpretation
A positive result indicates the presence of genetic variations associated with increased hypercholesterolemia susceptibility. This doesn’t guarantee you will develop high cholesterol, but signifies elevated risk that warrants proactive management through regular monitoring, lifestyle modifications, and potentially medication under medical supervision.
Negative Result Interpretation
A negative result suggests lower genetic predisposition to hypercholesterolemia related to PPP1R17 gene variations. However, other genetic and environmental factors can still influence cholesterol levels, so maintaining healthy lifestyle practices remains important.
Variant of Uncertain Significance (VUS)
Some genetic variations may have unknown clinical significance. In such cases, we provide guidance on monitoring and recommend follow-up testing as research advances.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | PPP1R17 Gene Hypercholesterolemia Susceptibility NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Methodology | Next-Generation Sequencing (NGS) Technology |
| Specialty | Metabolic Genetics |
Pre-Test Requirements
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential psychological impact of results
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities. Our network of certified collection centers ensures easy access to this advanced genetic testing regardless of your location.
Take Control of Your Cardiovascular Health Today
Don’t wait for symptoms to develop before addressing your cholesterol health. Our PPP1R17 Gene Hypercholesterolemia Susceptibility Test provides the genetic insights needed for proactive health management. With our special discounted price of only $500 USD, this comprehensive assessment offers exceptional value for understanding your genetic predisposition to cholesterol issues.
Ready to take the next step in personalized health management? Call our genetic specialists today at +1(267) 388-9828 to schedule your test or discuss any questions about genetic testing for hypercholesterolemia susceptibility. Our team is available to provide detailed information and help you make informed decisions about your cardiovascular health.
Early detection through genetic testing can be life-saving. Book your PPP1R17 Gene Hypercholesterolemia Susceptibility NGS Genetic DNA Test now and take the first step toward personalized cholesterol management and cardiovascular disease prevention.
