TFR2 Gene Hemochromatosis Type 3 NGS Genetic DNA Test

Comprehensive Genetic Testing for Hereditary Iron Overload Disorders

The TFR2 Gene Hemochromatosis Type 3 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary iron metabolism disorders. This advanced test specifically targets mutations in the transferrin receptor 2 (TFR2) gene, which plays a critical role in regulating iron homeostasis throughout the body. Hemochromatosis type 3 is an autosomal recessive condition characterized by excessive iron absorption from the diet, leading to progressive iron accumulation in vital organs including the liver, heart, pancreas, and endocrine glands.

What This Test Measures and Detects

Our state-of-the-art NGS Genetic DNA Test comprehensively analyzes the entire TFR2 gene sequence to identify pathogenic variants responsible for hemochromatosis type 3. The test specifically detects:

• Missense mutations affecting protein function
• Nonsense mutations leading to premature stop codons
• Frameshift mutations disrupting gene reading frames
• Splice site variants affecting mRNA processing
• Large deletions or duplications within the TFR2 gene

Using Next-Generation Sequencing technology, we achieve unparalleled accuracy in variant detection, providing clinicians with definitive genetic information for diagnosis and family counseling.

Who Should Consider This Test

This genetic test is particularly recommended for individuals experiencing:

• Unexplained chronic fatigue and weakness
• Persistent joint pain and arthritis-like symptoms
• Abnormal liver function tests without clear cause
• Bronze or gray skin discoloration
• Family history of iron overload disorders
• Elevated serum ferritin and transferrin saturation levels
• Early-onset diabetes or heart problems
• Unexplained abdominal pain or liver enlargement

Key Benefits of Genetic Testing

Early detection through genetic testing offers numerous advantages:

• Early Intervention: Identify at-risk individuals before symptom onset
• Personalized Treatment: Tailor therapeutic phlebotomy schedules based on genetic risk
• Family Planning: Provide accurate genetic counseling for family members
• Prevent Complications: Reduce risk of liver cirrhosis, diabetes, and heart failure
• Cost-Effective Management: Avoid expensive treatments for advanced disease complications

Understanding Your Test Results

Our comprehensive genetic report provides clear interpretation of your results:

• Positive Result: Indicates presence of pathogenic TFR2 mutations confirming hemochromatosis type 3 diagnosis
• Negative Result: No disease-causing variants detected, though clinical monitoring may still be recommended
• Variant of Uncertain Significance: Requires additional family studies and clinical correlation
• Carrier Status: Identifies individuals with single mutation who can pass the condition to offspring

All results include detailed explanations and recommendations for follow-up care with your healthcare provider.

Test Pricing Information

Nationwide Testing Availability

We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible testing for everyone.

Take Control of Your Health Today

Don’t wait for symptoms to progress. Early genetic testing for hemochromatosis type 3 can prevent serious health complications and provide peace of mind. Our experienced genetic counselors are available to discuss your results and create personalized management plans.

Call or WhatsApp us today at +1(267) 388-9828 to schedule your TFR2 Gene Hemochromatosis Type 3 NGS Genetic DNA Test and take the first step toward proactive health management.

Test Turnaround Time: 3-4 Weeks | Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card