ABCB4 Gene Gallbladder Disease Type 1 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Gallbladder and Liver Health
The ABCB4 Gene Gallbladder Disease Type 1 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for individuals suffering from unexplained gallbladder and liver disorders. This advanced genetic screening utilizes next-generation sequencing technology to identify mutations in the ABCB4 gene, which plays a critical role in bile transport and liver function. Understanding your genetic predisposition to gallbladder disease type 1 can provide life-changing insights for personalized medical management and preventive care strategies.
What Does This Test Measure and Detect?
This comprehensive genetic test specifically targets the ABCB4 gene, which encodes the multidrug resistance protein 3 (MDR3) responsible for transporting phospholipids into bile. The test detects:
- Pathogenic variants in the ABCB4 gene coding regions
- Mutations associated with progressive familial intrahepatic cholestasis type 3 (PFIC3)
- Genetic variations linked to low phospholipid-associated cholelithiasis syndrome
- Inherited defects affecting bile composition and flow
- Genetic markers for increased risk of gallbladder stones and liver damage
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Unexplained jaundice or persistent itching (pruritus)
- Recurrent abdominal pain in the right upper quadrant
- Abnormal liver function tests without clear cause
- Family history of gallbladder disease or liver disorders
- Early-onset gallbladder stones or biliary complications
- Children with progressive liver disease of unknown origin
- Individuals with elevated liver enzymes and bile duct abnormalities
Key Benefits of ABCB4 Genetic Testing
Undergoing this genetic analysis provides numerous advantages for your healthcare journey:
- Early Diagnosis: Identify genetic predisposition before severe symptoms develop
- Personalized Treatment: Guide medication choices and dietary recommendations
- Family Planning: Understand inheritance patterns for future generations
- Preventive Care: Implement lifestyle changes to reduce disease progression
- Peace of Mind: Resolve uncertainty about unexplained symptoms
- Comprehensive Analysis: NGS technology provides thorough genetic assessment
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and medical professionals:
- Positive Result: Indicates presence of ABCB4 gene mutation associated with gallbladder disease type 1. This information helps guide specific treatment approaches and monitoring protocols.
- Negative Result: Suggests no detectable ABCB4 mutations in the tested regions, though other genetic or environmental factors may still contribute to symptoms.
- Variant of Uncertain Significance: Some genetic changes may require additional family studies or research to determine clinical significance.
All results include detailed explanations and recommendations for follow-up care with your healthcare provider.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We have convenient testing locations across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our state-of-the-art facilities ensure accurate sample collection and processing with results typically available within 3-4 weeks.
Take Control of Your Genetic Health Today
Don’t let unexplained gallbladder or liver symptoms compromise your quality of life. The ABCB4 Gene Gallbladder Disease Type 1 NGS Genetic DNA Test provides the clarity you need to make informed healthcare decisions. Our experienced genetic counselors are available to discuss your results and provide personalized recommendations.
Ready to schedule your genetic test? Call us today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic health and preventing future complications.
Note: This test requires a blood sample and includes pre-test genetic counseling to review family history and create a comprehensive pedigree chart. Clinical history documentation is essential for accurate interpretation of results.
