F13B Gene Factor XIIIB Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Factor XIII Deficiency
The F13B Gene Factor XIIIB Deficiency NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying inherited bleeding disorders. Factor XIII deficiency is a rare autosomal recessive condition that significantly impacts the body’s ability to form stable blood clots. This advanced genetic test utilizes next-generation sequencing technology to provide precise detection of mutations in the F13B gene, enabling accurate diagnosis and personalized treatment strategies.
What Does This Test Measure and Detect?
This comprehensive genetic test specifically targets the F13B gene, which encodes the B-subunit of coagulation Factor XIII. The test detects:
- Point mutations and small insertions/deletions in the F13B gene
- Genetic variants affecting Factor XIIIB protein structure and function
- Inherited mutations responsible for impaired fibrin cross-linking
- Genetic markers associated with increased bleeding risk
- Carrier status for autosomal recessive inheritance patterns
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Unexplained or excessive bleeding following injuries or surgery
- Spontaneous bleeding episodes without apparent cause
- Abnormal bruising or hematoma formation
- Delayed wound healing or poor scar formation
- Family history of bleeding disorders or Factor XIII deficiency
- Umbilical stump bleeding in newborns
- Intracranial hemorrhage without trauma
Key Benefits of F13B Genetic Testing
- Accurate Diagnosis: Provides definitive genetic confirmation of Factor XIIIB deficiency
- Personalized Treatment: Enables targeted therapy with Factor XIII concentrates
- Family Planning: Identifies carrier status for informed reproductive decisions
- Proactive Management: Facilitates preventive measures before surgical procedures
- Genetic Counseling: Supports comprehensive family risk assessment
- Early Intervention: Allows timely treatment to prevent serious bleeding complications
Understanding Your Test Results
Your genetic test results will provide detailed information about:
- Positive Result: Identifies specific F13B gene mutations confirming Factor XIIIB deficiency diagnosis
- Negative Result: No pathogenic variants detected in the F13B gene analyzed
- Variant of Uncertain Significance: Genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Identifies individuals with one mutated copy who may pass the condition to offspring
All results are accompanied by comprehensive interpretation and recommendations from our genetic specialists. Positive findings typically indicate the need for Factor XIII replacement therapy and specialized hematology care.
Test Pricing Information
| Test Description | Price (USD) |
|---|---|
| F13B Gene Factor XIIIB Deficiency NGS Genetic DNA Test – Discount Price | $500 |
| F13B Gene Factor XIIIB Deficiency NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality results regardless of your location.
Take Control of Your Health Today
Don’t let uncertainty about bleeding disorders impact your quality of life. Our F13B Gene Factor XIIIB Deficiency NGS Genetic DNA Test provides the clarity needed for proper diagnosis and effective management. With results available in 3-4 weeks and multiple sample collection options (blood, extracted DNA, or FTA card), getting tested has never been more convenient.
Ready to schedule your genetic test? Contact our genetic counseling team today at +1(267) 388-9828 to discuss your testing options and schedule an appointment. Our specialists are available to answer your questions and guide you through the testing process with compassion and expertise.
Note: Pre-test requirements include providing clinical history and participating in a genetic counseling session to create a detailed family pedigree chart documenting relatives affected by Factor XIIIB deficiency.
