CYP2C19 Gene Poor Drug Metabolism NGS Genetic DNA Test
Understanding CYP2C19 Genetic Testing
The CYP2C19 Gene Poor Drug Metabolism NGS Genetic DNA Test represents a breakthrough in personalized medicine, offering crucial insights into how your body processes and responds to various medications. This advanced genetic analysis examines the CYP2C19 gene, which encodes an essential liver enzyme responsible for metabolizing approximately 10-15% of commonly prescribed drugs. Understanding your CYP2C19 genetic profile can significantly impact medication safety and effectiveness throughout your healthcare journey.
What Does the CYP2C19 Test Measure?
This comprehensive Next-Generation Sequencing (NGS) test identifies specific genetic variations in the CYP2C19 gene that determine your drug metabolism phenotype. The test detects:
- Normal metabolizer status (extensive metabolizers)
- Intermediate metabolizer status
- Poor metabolizer status
- Ultra-rapid metabolizer status
- Specific CYP2C19 gene variants and alleles
- Genetic polymorphisms affecting enzyme activity
Who Should Consider CYP2C19 Testing?
This genetic test is particularly valuable for individuals who:
- Experience unexpected side effects from standard medication doses
- Have a family history of adverse drug reactions
- Are starting new medications metabolized by CYP2C19
- Have experienced treatment failure with standard drug therapies
- Require medications for cardiovascular conditions, mental health, or gastrointestinal disorders
- Are planning long-term medication regimens
Medications Affected by CYP2C19 Metabolism
The CYP2C19 enzyme metabolizes numerous critical medications including:
- Clopidogrel (antiplatelet medication)
- Proton pump inhibitors (omeprazole, pantoprazole)
- Certain antidepressants (citalopram, sertraline)
- Anticonvulsants (phenytoin)
- Various benzodiazepines
Benefits of CYP2C19 Genetic Testing
Undergoing CYP2C19 genetic testing provides multiple significant advantages:
- Personalized Medication Dosing: Receive drug dosages tailored to your genetic metabolism capacity
- Reduced Adverse Reactions: Minimize the risk of medication side effects and toxicity
- Improved Treatment Outcomes: Enhance medication effectiveness through proper dosing
- Informed Medical Decisions: Empower healthcare providers with genetic insights for better prescribing
- Cost-Effective Healthcare: Avoid trial-and-error prescribing and associated healthcare costs
- Lifetime Application: Your genetic profile remains constant, providing lifelong medication guidance
Understanding Your Test Results
Your CYP2C19 test results will categorize you into one of four metabolic phenotypes:
Normal Metabolizer (Extensive Metabolizer)
You have normal CYP2C19 enzyme activity and will likely respond as expected to standard medication doses metabolized by this pathway.
Intermediate Metabolizer
You have reduced CYP2C19 enzyme activity and may require adjusted medication dosages or alternative drugs for optimal treatment outcomes.
Poor Metabolizer
You have significantly impaired CYP2C19 enzyme activity and are at increased risk for medication toxicity or treatment failure with standard doses of affected drugs.
Ultra-Rapid Metabolizer
You have enhanced CYP2C19 enzyme activity and may require higher medication doses or alternative therapies to achieve therapeutic effects.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | CYP2C19 Gene Poor Drug Metabolism NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before undergoing CYP2C19 genetic testing, we recommend:
- Providing complete clinical history relevant to medication responses
- Participating in a genetic counseling session
- Developing a pedigree chart of family members with medication sensitivity
- Consulting with your healthcare provider about current medications
Nationwide Testing Availability
We have testing facilities conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and many other cities. Our nationwide network ensures accessible genetic testing services for patients throughout the country.
Take Control of Your Medication Safety
Don’t leave your medication response to chance. The CYP2C19 Gene Poor Drug Metabolism NGS Genetic DNA Test provides scientifically validated insights that can transform your healthcare experience. By understanding your unique genetic makeup, you and your healthcare provider can make more informed decisions about medication selection and dosing.
Ready to optimize your medication therapy? Book your CYP2C19 genetic test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward personalized, safer medication management.
