ATP8B1 Gene Cholestasis Benign Recurrent Intrahepatic NGS Genetic DNA Test
Comprehensive Genetic Analysis for Liver Health
The ATP8B1 Gene Cholestasis Test represents a breakthrough in genetic diagnostics for liver disorders. This sophisticated NGS-based DNA analysis specifically targets mutations in the ATP8B1 gene, which plays a critical role in bile formation and liver function. Benign recurrent intrahepatic cholestasis (BRIC) is a rare inherited condition characterized by recurrent episodes of cholestasis without progression to chronic liver disease. Understanding your genetic predisposition through this test can provide life-changing insights into your liver health and enable proactive management strategies.
What This Advanced Genetic Test Detects
Our NGS genetic DNA test precisely identifies mutations in the ATP8B1 gene that are responsible for benign recurrent intrahepatic cholestasis. The test examines:
- Complete coding regions of the ATP8B1 gene
- Specific point mutations and small insertions/deletions
- Genetic variations affecting bile acid transport
- Inheritance patterns for family risk assessment
- Mutation types associated with disease severity
Who Should Consider This Genetic Test?
Clinical Indications and Symptoms
This genetic test is recommended for individuals experiencing:
- Recurrent episodes of jaundice without apparent cause
- Persistent itching (pruritus) during cholestatic episodes
- Unexplained elevations in liver enzymes (ALT, AST, ALP)
- Family history of similar liver symptoms
- Diagnostic uncertainty regarding liver function abnormalities
- Planning for pregnancy with personal or family history of cholestasis
Significant Benefits of Genetic Testing
Undergoing the ATP8B1 genetic test provides numerous advantages:
- Definitive Diagnosis: Eliminates diagnostic uncertainty and provides clear answers
- Personalized Treatment: Enables targeted management strategies for cholestatic episodes
- Family Planning: Provides crucial information for genetic counseling and family planning decisions
- Proactive Monitoring: Allows for early intervention during symptom-free periods
- Peace of Mind: Reduces anxiety through comprehensive genetic understanding
- Cost-Effective Care: Prevents unnecessary medical procedures and testing
Understanding Your Test Results
Interpretation Guidance
Your genetic test results will be carefully analyzed and explained by our expert genetic counselors:
- Positive Result: Indicates the presence of ATP8B1 gene mutations associated with BRIC, confirming the diagnosis and enabling targeted management
- Negative Result: Suggests that ATP8B1 mutations are not the cause of symptoms, directing further diagnostic evaluation
- Variant of Uncertain Significance: Identifies genetic changes requiring additional clinical correlation and family studies
- Carrier Status: Determines if you carry a single copy of the mutation, important for family planning decisions
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | ATP8B1 Gene Cholestasis Benign Recurrent Intrahepatic NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take Control of Your Liver Health Today
Don’t let uncertainty about your liver symptoms continue. The ATP8B1 genetic test provides definitive answers and empowers you with knowledge about your genetic health. Our experienced genetic counselors are available to discuss your results and provide comprehensive guidance for managing benign recurrent intrahepatic cholestasis.
Ready to begin your genetic health journey? Book your ATP8B1 Gene Cholestasis Test today by calling our dedicated genetic testing specialists at +1(267) 388-9828 or schedule your appointment online. Take the first step toward understanding your genetic predisposition and optimizing your liver health management.
