UPD Chromosome 6 Gene 6q24-Related Transient Neonatal Diabetes Mellitus Type 1 NGS Genetic DNA Test
Understanding Transient Neonatal Diabetes Mellitus Type 1
Transient Neonatal Diabetes Mellitus Type 1 (TNDM1) represents a rare but significant metabolic disorder affecting newborns during their first weeks of life. This condition is characterized by temporary insulin deficiency and hyperglycemia that typically resolves within the first year, though affected individuals may develop type 2 diabetes later in life. The UPD Chromosome 6 Gene 6q24-Related NGS Genetic DNA Test provides comprehensive genetic analysis to identify the underlying causes of this complex condition.
What This Advanced Genetic Test Detects
Our specialized NGS-based genetic test focuses on identifying specific genetic abnormalities in the 6q24 chromosomal region, including:
- Uniparental Disomy (UPD) of chromosome 6
- Methylation defects affecting imprinted genes
- Mutations in the PLAGL1 and HYMAI genes
- Chromosomal rearrangements involving the 6q24 region
- Epigenetic modifications impacting gene expression
Clinical Indications and Who Should Consider Testing
This genetic test is particularly recommended for:
- Newborns presenting with unexplained hyperglycemia or diabetes symptoms
- Infants with intrauterine growth restriction and subsequent diabetes diagnosis
- Families with a history of transient neonatal diabetes
- Cases where maternal uniparental disomy is suspected
- Patients with unexplained developmental delays alongside diabetes symptoms
- Individuals planning pregnancy with family history of neonatal diabetes
Key Benefits of Genetic Testing for TNDM1
Early genetic diagnosis through our comprehensive NGS testing offers numerous advantages:
- Accurate Diagnosis: Provides definitive identification of 6q24-related diabetes causes
- Personalized Treatment: Enables tailored insulin therapy and monitoring protocols
- Family Planning Guidance: Offers recurrence risk assessment for future pregnancies
- Long-term Health Management: Facilitates appropriate follow-up care and diabetes screening
- Genetic Counseling Support: Provides comprehensive family risk assessment
Understanding Your Test Results
Our genetic counselors provide detailed interpretation of your results, including:
- Clear explanation of identified genetic variants and their clinical significance
- Guidance on treatment implications and management strategies
- Information about recurrence risks for family members
- Recommendations for ongoing monitoring and specialist consultations
- Support resources for families affected by neonatal diabetes
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic testing facilities ensures accessible, reliable service nationwide.
Take Action for Your Child’s Health
Don’t wait to get answers about neonatal diabetes concerns. Our expert team is ready to provide comprehensive genetic testing and support. Contact us today to schedule your UPD Chromosome 6 Gene 6q24-Related Transient Neonatal Diabetes Mellitus Type 1 NGS Genetic DNA Test.
Call or WhatsApp: +1(267) 388-9828 to book your test consultation and take the first step toward definitive diagnosis and personalized care.
