AR Gene Spinal and Bulbar Muscular Atrophy X-Linked NGS Genetic DNA Test
Comprehensive Genetic Testing for Neuromuscular Disorders
The AR Gene Spinal and Bulbar Muscular Atrophy X-Linked NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for neuromuscular conditions. This sophisticated test specifically targets mutations in the androgen receptor (AR) gene located on the X chromosome, which are responsible for X-linked spinal and bulbar muscular atrophy, commonly known as Kennedy’s disease. This progressive neurodegenerative disorder affects motor neurons in the spinal cord and brainstem, leading to significant muscle weakness and atrophy.
What This Advanced Genetic Test Detects
Our NGS-based genetic test precisely identifies CAG trinucleotide repeat expansions in the AR gene, which is the primary genetic abnormality causing Kennedy’s disease. The test measures:
- CAG repeat length in exon 1 of the androgen receptor gene
- Presence of expanded CAG repeats beyond the normal range (typically 38-62 repeats in affected individuals)
- Genetic confirmation of X-linked inheritance pattern
- Risk assessment for disease progression and severity
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Progressive muscle weakness in limbs, particularly in the proximal muscles
- Difficulty with swallowing (dysphagia) and speech articulation
- Muscle cramps and fasciculations (muscle twitching)
- Family history of similar neuromuscular symptoms
- Male individuals with suspected X-linked inheritance patterns
- Unexplained elevated creatine kinase levels
- Progressive bulbar symptoms including facial weakness
Significant Benefits of Genetic Testing
Undergoing the AR Gene Spinal and Bulbar Muscular Atrophy test provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out Kennedy’s disease with high precision
- Early Intervention: Enables proactive management strategies before significant disability develops
- Genetic Counseling: Provides essential information for family planning and risk assessment
- Treatment Guidance: Helps neurologists develop targeted management plans
- Prognostic Information: Offers insights into potential disease progression
- Peace of Mind: Reduces diagnostic uncertainty for patients and families
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and neurologists:
- Normal Range: CAG repeats typically between 9-36 indicate no increased risk for Kennedy’s disease
- Intermediate Range: Repeats between 37-38 may require clinical correlation and follow-up
- Affected Range: CAG repeats of 38-62 confirm diagnosis of spinal and bulbar muscular atrophy
- Genetic Counseling: All positive results include comprehensive counseling sessions
- Family Testing: Recommendations for testing at-risk family members when indicated
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Accessibility
We have conveniently located branches across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality genetic testing services nationwide.
Take Control of Your Neurological Health Today
Don’t let uncertainty about neuromuscular symptoms affect your quality of life. Our AR Gene Spinal and Bulbar Muscular Atrophy X-Linked NGS Genetic DNA Test provides the clarity you need for informed healthcare decisions. With results available in 3-4 weeks and multiple sample collection options including blood, extracted DNA, or FTA card blood spots, getting tested has never been more convenient.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book this essential diagnostic test. Our team of genetic specialists and neurologists is ready to guide you through every step of the testing process.
