C19orf12 Gene SPG43 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Spastic Paraplegia
The C19orf12 Gene SPG43 NGS Genetic DNA Test represents a significant advancement in neurological genetic diagnostics, offering precise detection of mutations associated with hereditary spastic paraplegia type 43. This sophisticated testing methodology provides crucial insights for patients and healthcare providers navigating complex neurological conditions.
What This Test Measures and Detects
This specialized genetic test focuses on identifying mutations within the C19orf12 gene, which plays a critical role in neurological function and cellular metabolism. The test specifically targets:
- Point mutations and small insertions/deletions in the C19orf12 gene
- Genetic variants associated with SPG43 hereditary spastic paraplegia
- Pathogenic mutations that disrupt normal neurological development
- Inheritance patterns for genetic counseling purposes
Using next-generation sequencing technology, the test provides comprehensive coverage of the entire C19orf12 gene coding region, ensuring high accuracy and reliability in mutation detection.
Who Should Consider This Test
This genetic test is particularly recommended for individuals experiencing:
- Progressive leg weakness and stiffness beginning in childhood or early adulthood
- Difficulty walking with increased muscle tone and spasticity
- Family history of hereditary spastic paraplegia or similar neurological conditions
- Unexplained progressive mobility challenges
- Early-onset spasticity without clear diagnosis
- Consanguineous family backgrounds with neurological symptoms
Clinical Benefits and Importance
Undergoing the C19orf12 Gene SPG43 test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out SPG43 hereditary spastic paraplegia
- Treatment Guidance: Informs targeted therapeutic approaches and management strategies
- Genetic Counseling: Provides essential information for family planning decisions
- Prognostic Insights: Helps predict disease progression and potential complications
- Family Risk Assessment: Identifies at-risk relatives who may benefit from testing
- Research Contribution: Advances understanding of rare neurological disorders
Understanding Your Test Results
Your genetic test results will be carefully analyzed and interpreted by our team of certified genetic specialists. Results typically fall into three categories:
- Positive Result: Indicates the presence of a pathogenic mutation in the C19orf12 gene, confirming SPG43 diagnosis
- Negative Result: Suggests no detectable mutations in the tested gene, though other genetic causes may need investigation
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
All results include comprehensive genetic counseling to ensure proper understanding and appropriate next steps for medical management.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | C19orf12 Gene SPG43 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure you have:
- Complete clinical history documentation
- Scheduled genetic counseling session
- Family pedigree chart detailing affected relatives
- Physician referral when required
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing regardless of your location.
Take the Next Step Toward Clarity
Don’t let uncertainty about neurological symptoms affect your quality of life. The C19orf12 Gene SPG43 NGS Genetic DNA Test provides the answers you need for informed medical decisions and personalized care planning.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment or to speak with our genetic counseling team. Take control of your neurological health with comprehensive genetic insights from America’s trusted genetic testing provider.
