PSEN1 Gene Pick’s Disease NGS Genetic DNA Test
Comprehensive Genetic Testing for Early-Onset Neurological Disorders
The PSEN1 Gene Pick’s Disease NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise detection of mutations in the Presenilin 1 (PSEN1) gene. This advanced test utilizes Next-Generation Sequencing technology to provide comprehensive analysis of genetic variations associated with early-onset Alzheimer’s disease and Pick’s disease, enabling early intervention and personalized treatment strategies.
What Does This Test Measure and Detect?
This sophisticated genetic test specifically targets the PSEN1 gene, which plays a critical role in amyloid precursor protein processing. The test detects:
- Pathogenic mutations in the PSEN1 gene associated with autosomal dominant Alzheimer’s disease
- Genetic variants linked to early-onset dementia and cognitive decline
- Mutations contributing to Pick’s disease pathology
- Single nucleotide polymorphisms (SNPs) and copy number variations (CNVs)
- Both known and novel genetic alterations affecting neurological function
Who Should Consider PSEN1 Genetic Testing?
This test is particularly recommended for individuals experiencing:
- Early-onset memory loss or cognitive decline before age 65
- Family history of Alzheimer’s disease in multiple generations
- Unexplained behavioral changes or personality alterations
- Progressive language difficulties or executive function impairment
- Strong family history of dementia with early onset
- Individuals planning family who have relatives with PSEN1 mutations
Clinical Benefits of PSEN1 Genetic Testing
Undergoing PSEN1 genetic testing provides numerous advantages for patients and healthcare providers:
- Early Diagnosis: Enables detection of genetic predisposition before symptom onset
- Personalized Treatment: Guides targeted therapeutic interventions and medication selection
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Proactive Management: Allows for early implementation of cognitive preservation strategies
- Clinical Trial Eligibility: May qualify patients for cutting-edge Alzheimer’s research studies
- Peace of Mind: Reduces uncertainty and enables informed healthcare decisions
Understanding Your Test Results
Your PSEN1 genetic test results will be carefully interpreted by our team of certified genetic counselors and neurologists:
- Positive Result: Indicates presence of a known pathogenic PSEN1 mutation, significantly increasing Alzheimer’s disease risk
- Negative Result: No detected PSEN1 mutations, though other genetic or environmental factors may still contribute to risk
- Variant of Uncertain Significance (VUS): Identifies genetic changes with unknown clinical significance requiring further research
- Comprehensive Report: Includes detailed interpretation, clinical implications, and recommended next steps
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Convenient Testing Locations Across USA
We have established testing facilities in all major metropolitan areas throughout the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible genetic testing services with consistent quality standards and professional genetic counseling support.
Pre-Test Requirements
Before undergoing PSEN1 genetic testing, patients should complete:
- Comprehensive clinical history documentation
- Genetic counseling session with certified genetic counselor
- Development of detailed family pedigree chart
- Discussion of test implications, benefits, and limitations
- Informed consent process addressing psychological and privacy considerations
Take Control of Your Neurological Health Today
Early detection through PSEN1 genetic testing can significantly impact treatment outcomes and quality of life. Our team of neurological genetics specialists is ready to guide you through the testing process and provide comprehensive support for result interpretation and next steps.
Book your PSEN1 Gene Pick’s Disease NGS Genetic DNA Test today by calling +1(267) 388-9828 or scheduling your appointment online. Take the first step toward understanding your genetic risk and implementing proactive neurological health strategies.
