CTNNA2 Gene Neuronal Migration Disorder NGS Genetic DNA Test
Comprehensive Genetic Testing for Neurological Development Disorders
The CTNNA2 Gene Neuronal Migration Disorder NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise identification of mutations associated with brain development abnormalities. This advanced testing methodology provides critical insights for patients and families affected by neuronal migration disorders, enabling early intervention and personalized treatment strategies.
What is Neuronal Migration and Why CTNNA2 Matters?
Neuronal migration is a fundamental process during brain development where nerve cells travel from their origin to their final positions in the brain. The CTNNA2 gene encodes alpha-catenin 2, a protein crucial for cell adhesion and migration processes. When mutations occur in this gene, they disrupt normal neuronal migration patterns, leading to structural brain abnormalities and subsequent neurological symptoms.
What Does the CTNNA2 Gene Test Detect?
Our comprehensive NGS-based genetic test specifically targets:
- Point mutations in the CTNNA2 gene
- Small insertions and deletions affecting gene function
- Copy number variations impacting neuronal development
- Pathogenic variants associated with cortical malformations
- Genetic markers linked to lissencephaly and other migration disorders
Advanced NGS Technology for Precision Diagnosis
Utilizing cutting-edge Next-Generation Sequencing technology, our test provides comprehensive coverage of the CTNNA2 gene with exceptional accuracy. This approach enables detection of even rare genetic variants that conventional testing methods might miss, ensuring thorough assessment of potential neurological risks.
Who Should Consider CTNNA2 Genetic Testing?
Clinical Indications and Symptoms
This test is particularly recommended for individuals presenting with:
- Unexplained developmental delays in infancy or childhood
- Recurrent seizures or epilepsy of unknown origin
- Intellectual disability without clear cause
- Abnormal brain imaging findings suggesting migration disorders
- Family history of neurological conditions
- Cortical malformations detected through MRI scans
- Motor coordination difficulties and movement disorders
- Speech and language development concerns
Family Planning Considerations
Couples with family history of neuronal migration disorders should consider pre-conception genetic testing to assess inheritance risks and make informed reproductive decisions.
Significant Benefits of CTNNA2 Genetic Testing
Early Diagnosis and Intervention
Early identification of CTNNA2 mutations enables:
- Timely implementation of targeted therapeutic interventions
- Personalized neurological management strategies
- Appropriate educational and developmental support planning
- Optimized seizure management protocols
Family Risk Assessment
Genetic testing provides crucial information for:
- Determining inheritance patterns within families
- Assessing recurrence risks for future pregnancies
- Enabling informed family planning decisions
- Identifying at-risk family members for preventive monitoring
Research and Clinical Advancements
Participation in genetic testing contributes to ongoing research efforts, helping advance understanding of neuronal migration disorders and developing new treatment approaches.
Understanding Your Test Results
Interpretation Guidelines
Our comprehensive results report includes:
- Positive Result: Indicates presence of pathogenic CTNNA2 mutation. Consultation with neurologist and genetic counselor recommended for management planning.
- Negative Result: No disease-causing mutations detected in CTNNA2 gene. Other genetic or environmental factors may need investigation.
- Variant of Uncertain Significance: Genetic change identified with unclear clinical impact. Ongoing monitoring and family studies may be recommended.
Post-Test Counseling Support
All patients receive detailed genetic counseling to help understand results implications, discuss management options, and address family planning considerations.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | CTNNA2 Gene Neuronal Migration Disorder NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Neurology and Genetics |
Pre-Test Requirements
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Review of previous neurological evaluations and imaging studies
- Discussion of testing implications and potential outcomes
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified collection centers ensures accessible testing regardless of your location.
Take Control of Your Neurological Health
Don’t let uncertainty about neurological symptoms affect your quality of life. Our CTNNA2 Gene Neuronal Migration Disorder NGS Genetic DNA Test provides the clarity needed for informed healthcare decisions and personalized treatment approaches.
Ready to Schedule Your Test?
Contact our genetic specialists today to discuss your testing needs and schedule an appointment. Call or WhatsApp us at +1(267) 388-9828 to book your comprehensive neurological genetic assessment.
Take the first step toward understanding your neurological health and securing your family’s genetic future.
