SUCLA2 Gene Mitochondrial DNA Depletion Syndrome NGS Genetic DNA Test
Understanding Mitochondrial DNA Depletion Syndrome
Mitochondrial DNA depletion syndrome represents a group of severe genetic disorders characterized by a significant reduction in mitochondrial DNA copy number in affected tissues. The SUCLA2 gene plays a critical role in mitochondrial energy production, and mutations in this gene can lead to devastating neurological consequences. Our advanced NGS genetic testing provides comprehensive analysis to identify these mutations with exceptional accuracy.
What This Test Measures and Detects
The SUCLA2 Gene Mitochondrial DNA Depletion Syndrome NGS Genetic DNA Test specifically targets:
- Complete sequencing of the SUCLA2 gene using Next-Generation Sequencing technology
- Detection of point mutations, deletions, and insertions within the gene
- Identification of pathogenic variants associated with mitochondrial DNA depletion
- Analysis of gene regions critical for succinate-CoA ligase function
- Comprehensive variant interpretation by certified genetic specialists
Who Should Consider This Test
Clinical Indications and Symptoms
This test is recommended for individuals presenting with:
- Unexplained neurological deterioration in infancy or early childhood
- Progressive muscle weakness and hypotonia
- Developmental regression or delayed milestones
- Movement disorders including dystonia and ataxia
- Hearing loss or vision problems of unknown origin
- Family history of mitochondrial disorders or consanguinity
- Metabolic abnormalities suggestive of mitochondrial dysfunction
- Failure to thrive despite adequate nutrition
Benefits of Taking the SUCLA2 Genetic Test
Early and accurate diagnosis through our specialized testing offers numerous advantages:
- Precise Diagnosis: Eliminates diagnostic uncertainty and enables targeted treatment approaches
- Family Planning Guidance: Provides crucial information for reproductive decisions and genetic counseling
- Personalized Management: Allows for tailored therapeutic interventions and symptom management
- Prognostic Information: Helps healthcare providers anticipate disease progression and complications
- Research Contribution: Advances scientific understanding of mitochondrial disorders
- Peace of Mind: Reduces anxiety associated with undiagnosed symptoms
Understanding Your Test Results
Our comprehensive genetic testing provides detailed insights into your mitochondrial health:
Positive Result Interpretation
A positive result indicates the presence of pathogenic mutations in the SUCLA2 gene. This confirmation enables:
- Implementation of specialized mitochondrial support therapies
- Development of personalized neurological care plans
- Family member screening and genetic counseling
- Connection with specialized mitochondrial disease centers
Negative Result Interpretation
A negative result suggests that SUCLA2 mutations are not the cause of symptoms, guiding physicians toward alternative diagnostic pathways while providing reassurance about this specific genetic condition.
Variant of Uncertain Significance
In cases where genetic variants of uncertain significance are identified, our genetic counseling team provides comprehensive guidance and may recommend additional family studies or periodic re-evaluation as scientific knowledge advances.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | SUCLA2 Gene Mitochondrial DNA Depletion Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing regardless of your location.
Take the Next Step Toward Diagnosis
Don’t let unexplained neurological symptoms remain a mystery. Our specialized genetic testing provides the answers you need for proper diagnosis and management. Contact our genetic counseling team today to schedule your test and begin your journey toward clarity and appropriate care.
Call or WhatsApp us now at +1(267) 388-9828 to book your SUCLA2 Gene Mitochondrial DNA Depletion Syndrome NGS Genetic DNA Test and take control of your neurological health.
