MT-TS1 Gene MERRF/MELAS Overlap Syndrome NGS Genetic DNA Test
Comprehensive Mitochondrial Disorder Diagnosis
The MT-TS1 Gene MERRF/MELAS Overlap Syndrome NGS Genetic DNA Test represents a breakthrough in mitochondrial disorder diagnostics, offering precise identification of genetic mutations responsible for complex neurological conditions. This advanced testing methodology provides critical insights into mitochondrial DNA variations that disrupt cellular energy production, particularly affecting the nervous system and muscular function.
What This Test Measures and Detects
This sophisticated genetic analysis specifically targets the mitochondrial MT-TS1 gene, which encodes the mitochondrial transfer RNA for serine. The test utilizes next-generation sequencing technology to identify:
- Point mutations in the MT-TS1 gene associated with MERRF/MELAS overlap syndrome
- Genetic variations affecting mitochondrial protein synthesis
- Mutations that impair cellular energy production in neurological tissues
- Specific nucleotide changes linked to mitochondrial encephalomyopathies
- Genetic markers for progressive neurological deterioration
Who Should Consider This Test
This genetic test is particularly recommended for individuals experiencing:
- Unexplained neurological symptoms including seizures and myoclonus
- Progressive muscle weakness and exercise intolerance
- Recurrent stroke-like episodes without vascular cause
- Developmental delays or regression in children
- Family history of mitochondrial disorders
- Unexplained lactic acidosis or metabolic abnormalities
- Vision or hearing problems of unknown origin
- Multiple organ system involvement suggesting mitochondrial disease
Clinical Benefits of Genetic Testing
Undergoing the MT-TS1 genetic test provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Provides definitive identification of mitochondrial DNA mutations
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning Guidance: Offers crucial information for genetic counseling and reproductive decisions
- Prognostic Information: Helps predict disease progression and potential complications
- Early Intervention: Facilitates timely management strategies to slow disease progression
- Differential Diagnosis: Distinguishes between various mitochondrial disorders with overlapping symptoms
Understanding Your Test Results
Our comprehensive genetic counseling service helps you interpret your results effectively:
- Positive Result: Indicates the presence of MT-TS1 gene mutations associated with MERRF/MELAS overlap syndrome, requiring specialized neurological care and mitochondrial support
- Negative Result: Suggests alternative causes for symptoms, guiding further diagnostic evaluation
- Variant of Uncertain Significance: Identifies genetic changes requiring additional research and clinical correlation
- Carrier Status: Provides information about inheritance patterns and family risk assessment
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States, with specialized facilities in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and neurological specialists ensures accessible, high-quality care regardless of your location.
Take Control of Your Neurological Health
Early genetic testing for mitochondrial disorders can significantly impact treatment outcomes and quality of life. Our team of board-certified genetic counselors and neurological specialists provides comprehensive support throughout your testing journey, from initial consultation to result interpretation and ongoing management strategies.
Ready to schedule your MT-TS1 genetic test? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online to begin your journey toward accurate diagnosis and personalized care.
