DLG3 Gene Mental Retardation X-Linked Type 90 NGS Genetic DNA Test
Comprehensive Genetic Testing for X-Linked Intellectual Disability
The DLG3 Gene Mental Retardation X-Linked Type 90 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying the genetic basis of X-linked intellectual disability. This specialized test focuses on the DLG3 gene, which plays a critical role in neurological development and synaptic function. When mutations occur in this gene, they can lead to significant cognitive impairments and developmental challenges, primarily affecting males due to the X-linked inheritance pattern.
What Does This Test Measure and Detect?
This advanced genetic test utilizes Next Generation Sequencing (NGS) technology to comprehensively analyze the DLG3 gene for pathogenic variants. The test specifically detects:
- Point mutations and single nucleotide variants in the DLG3 gene
- Small insertions and deletions affecting gene function
- Copy number variations that may impact gene expression
- Specific genetic markers associated with X-linked type 90 mental retardation
- Inheritance patterns consistent with X-linked transmission
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals and families experiencing:
- Unexplained intellectual disability or developmental delays in males
- Family history suggesting X-linked inheritance of cognitive impairments
- Children with speech and language development delays
- Individuals with learning difficulties and behavioral challenges
- Families planning pregnancy with known X-linked intellectual disability history
- Patients with neurological symptoms without clear diagnosis
Clinical Symptoms and Indications
Patients who may benefit from DLG3 genetic testing typically present with:
- Moderate to severe intellectual disability
- Delayed motor skill development
- Speech and language acquisition difficulties
- Behavioral abnormalities including autism spectrum features
- Seizures or epilepsy in some cases
- Distinct facial features in certain individuals
Benefits of DLG3 Genetic Testing
Undergoing DLG3 gene testing provides numerous advantages for patients and families:
- Accurate Diagnosis: Provides definitive genetic confirmation of X-linked mental retardation type 90
- Family Planning Guidance: Enables informed reproductive decisions for carrier females
- Personalized Management: Guides appropriate educational and therapeutic interventions
- Prognostic Information: Helps understand the expected disease progression and outcomes
- Genetic Counseling: Supports families in understanding inheritance patterns and recurrence risks
- Early Intervention: Facilitates timely implementation of support services and therapies
Understanding Your Test Results
Positive Result Interpretation
A positive result indicates the presence of a pathogenic mutation in the DLG3 gene. This confirms the diagnosis of X-linked mental retardation type 90 and provides:
- Definitive explanation for the patient’s neurological symptoms
- Clear inheritance pattern information for family members
- Basis for targeted management and support strategies
- Opportunity for carrier testing in female relatives
Negative Result Interpretation
A negative result suggests that no pathogenic mutations were detected in the DLG3 gene. However, this does not completely rule out genetic causes, as:
- Other genetic conditions may cause similar symptoms
- Rare mutations not detected by current technology may be present
- Further genetic testing may be recommended based on clinical presentation
Variant of Uncertain Significance (VUS)
Some results may identify genetic changes with unclear clinical significance. In such cases:
- Additional family member testing may be recommended
- Ongoing research may provide future clarification
- Clinical correlation with symptoms remains essential
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | DLG3 Gene Mental Retardation X-Linked Type 90 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
| Specialty | Neurology and Genetics |
Pre-Test Requirements and Preparation
Before undergoing DLG3 genetic testing, patients should complete:
- Comprehensive clinical history documentation
- Genetic counseling session with a certified genetic counselor
- Development of a detailed pedigree chart documenting affected family members
- Discussion of testing implications, benefits, and limitations
- Informed consent process explaining potential outcomes
Nationwide Testing Availability
We proudly offer DLG3 genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and neurological specialists ensures comprehensive care and support throughout the testing process.
Take the Next Step Toward Genetic Clarity
If you or a family member are experiencing symptoms of unexplained intellectual disability or have a family history suggesting X-linked inheritance patterns, the DLG3 Gene Mental Retardation X-Linked Type 90 NGS Genetic DNA Test can provide the answers you need. Our team of neurological genetics specialists is ready to guide you through the testing process and help you understand your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic consultation and book your test. Take control of your genetic health with advanced diagnostic testing from America’s leading genetics corporation.
