GRIN2B Gene Mental Retardation Autosomal Dominant Type 6 NGS Genetic DNA Test
Comprehensive Genetic Testing for Neurological Development Disorders
The GRIN2B Gene Mental Retardation Autosomal Dominant Type 6 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying mutations in the GRIN2B gene, which plays a critical role in brain development and cognitive function. This specialized genetic examination utilizes next-generation sequencing technology to provide comprehensive analysis of the GRIN2B gene, offering families and healthcare providers definitive answers about neurological conditions affecting intellectual development.
What Does the GRIN2B Gene Test Measure?
This advanced genetic test specifically targets the GRIN2B gene, which encodes the GluN2B subunit of the NMDA (N-methyl-D-aspartate) receptor. The NMDA receptor is essential for synaptic plasticity, learning, memory formation, and proper neural development. The test detects:
- Pathogenic variants and mutations in the GRIN2B gene
- Single nucleotide variants (SNVs) affecting protein function
- Small insertions and deletions (indels) disrupting gene expression
- Copy number variations impacting gene dosage
- Novel mutations associated with neurological phenotypes
Who Should Consider GRIN2B Genetic Testing?
This test is particularly recommended for individuals presenting with:
- Unexplained intellectual disability or developmental delay
- Autism spectrum disorder features with intellectual impairment
- Speech and language development delays
- Motor coordination difficulties and movement disorders
- Seizures or epilepsy of unknown origin
- Behavioral abnormalities including attention deficits
- Family history of autosomal dominant intellectual disability
- Previous negative genetic testing results with strong clinical suspicion
Clinical Benefits of GRIN2B Gene Testing
Undergoing GRIN2B genetic testing provides numerous advantages for patients and families:
- Accurate Diagnosis: Provides definitive molecular confirmation of GRIN2B-related disorders
- Personalized Treatment: Enables targeted therapeutic interventions based on specific mutation
- Family Planning: Offers crucial information for reproductive decision-making
- Prognostic Insights: Helps predict disease progression and potential complications
- Early Intervention: Facilitates timely implementation of developmental support services
- Genetic Counseling: Provides comprehensive family risk assessment and management
Understanding Your Test Results
Your GRIN2B genetic test results will be thoroughly explained by our certified genetic counselors:
- Positive Result: Indicates a pathogenic mutation in the GRIN2B gene, confirming the diagnosis of autosomal dominant mental retardation type 6
- Negative Result: Suggests no disease-causing mutations were detected in the GRIN2B gene
- Variant of Uncertain Significance (VUS): Identifies a genetic change whose clinical significance is currently unknown
- Carrier Status: Determines inheritance patterns and recurrence risks for family members
All results include detailed interpretation and recommendations for next steps in clinical management.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| GRIN2B Gene Mental Retardation Autosomal Dominant Type 6 NGS Genetic DNA Test – Discount Price | $500 |
| GRIN2B Gene Mental Retardation Autosomal Dominant Type 6 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
General Genetics Corporation provides comprehensive GRIN2B genetic testing services across the United States. We have established testing facilities and collection centers in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to advanced genetic diagnostics regardless of your location.
Take the Next Step Toward Genetic Clarity
If you or your family member is experiencing symptoms suggestive of GRIN2B-related disorders, don’t wait to get answers. Our team of genetic specialists, neurologists, and certified genetic counselors are ready to provide comprehensive testing and support.
Call us today at +1(267) 388-9828 to schedule your GRIN2B genetic test or to speak with our genetic counseling team. Early diagnosis can make a significant difference in management and quality of life.
Remember: Genetic testing for neurological disorders provides not just answers, but pathways to better management, targeted therapies, and informed family planning decisions. Take control of your genetic health today.
