SCN9A Gene Insensitivity to Pain Channelopathy-Associated NGS Genetic DNA Test
Understanding SCN9A Gene Insensitivity to Pain
The SCN9A Gene Insensitivity to Pain Channelopathy-Associated NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics. This specialized test focuses on identifying mutations in the SCN9A gene, which encodes the Nav1.7 sodium channel protein crucial for pain signal transmission in the peripheral nervous system. When this gene malfunctions, individuals may experience congenital insensitivity to pain—a rare condition that prevents normal pain perception and can lead to serious health complications.
What Does This Test Measure?
Our advanced NGS genetic DNA test specifically targets:
- Complete sequencing of the SCN9A gene to identify pathogenic variants
- Detection of missense, nonsense, frameshift, and splice-site mutations
- Analysis of channelopathy-associated genetic alterations
- Identification of both inherited and de novo mutations
- Comprehensive coverage of all coding regions and critical regulatory elements
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Congenital absence of pain perception since birth
- Recurrent injuries without appropriate pain response
- Family history of pain insensitivity disorders
- Unexplained fractures, burns, or tissue damage
- Delayed recognition of infections or inflammatory conditions
- Associated symptoms like anosmia (loss of smell) or autonomic dysfunction
Clinical Indications and Symptoms
Patients presenting with these neurological symptoms should consider testing:
- Complete or partial inability to perceive painful stimuli
- History of self-mutilation behaviors in childhood
- Multiple orthopedic complications without pain complaints
- Temperature perception abnormalities
- Associated neuropathies or autonomic nervous system issues
Benefits of SCN9A Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Definitive Diagnosis: Confirms or rules out SCN9A-related channelopathies
- Personalized Management: Enables tailored treatment and preventive strategies
- Family Planning: Provides crucial information for genetic counseling
- Early Intervention: Facilitates proactive management of potential complications
- Research Contribution: Helps advance understanding of rare pain disorders
- Medical Guidance: Informs appropriate safety measures and monitoring protocols
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert team:
- Positive Result: Indicates identified pathogenic mutation in SCN9A gene, confirming diagnosis
- Negative Result: Suggests absence of detectable SCN9A mutations, though other genetic causes may exist
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals who may pass the condition to offspring
All results include comprehensive genetic counseling to ensure proper understanding and next steps.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| SCN9A Gene Insensitivity to Pain Channelopathy-Associated NGS Genetic DNA Test | $500 (Discounted from $700) |
| Regular Price | $700 |
| Discount Price | $500 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Pre-Test Requirements
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session with our specialists
- Development of detailed family pedigree chart
- Discussion of testing implications and potential outcomes
- Informed consent process
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take the Next Step Toward Diagnosis
If you or a loved one experiences symptoms of pain insensitivity, don’t wait to get answers. Our specialized SCN9A genetic testing provides the clarity needed for proper diagnosis and management. With our discounted price of only $500 and comprehensive genetic counseling support, you can take control of your neurological health.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or learn more about this essential genetic test. Our genetic specialists are ready to help you understand your condition and develop an appropriate care plan.
Early diagnosis through advanced genetic testing can significantly improve quality of life and prevent serious complications associated with congenital insensitivity to pain. Trust our expertise in neurological genetics to provide the answers you need.
