SCN1A Gene Generalized Epilepsy with Febrile Seizures Plus Type 2 NGS Genetic DNA Test
Understanding SCN1A Gene Testing for Epilepsy Disorders
The SCN1A Gene Generalized Epilepsy with Febrile Seizures Plus Type 2 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics. This specialized test focuses on identifying mutations in the SCN1A gene, which plays a critical role in sodium channel function within the nervous system. Sodium channels are essential for proper neuronal signaling, and disruptions in the SCN1A gene can lead to various forms of epilepsy and seizure disorders.
What Does the SCN1A Gene Test Measure?
This comprehensive genetic analysis specifically targets:
- Detection of pathogenic variants in the SCN1A gene
- Identification of mutations associated with Generalized Epilepsy with Febrile Seizures Plus (GEFS+) type 2
- Analysis of sodium channel protein encoding regions
- Assessment of genetic markers linked to seizure susceptibility
- Evaluation of inherited and de novo mutations
Who Should Consider SCN1A Genetic Testing?
This test is particularly recommended for individuals experiencing:
- Recurrent febrile seizures beyond typical childhood age
- Multiple seizure types including generalized tonic-clonic seizures
- Family history of epilepsy or seizure disorders
- Unexplained neurological symptoms in childhood
- Resistance to standard anti-epileptic medications
- Developmental delays associated with seizure activity
Clinical Indications and Symptoms
Patients presenting with the following symptoms may benefit from SCN1A testing:
- Febrile seizures persisting beyond age 6
- Multiple seizure types within the same individual
- Absence seizures, myoclonic seizures, or atonic seizures
- Family history spanning multiple generations
- Neurological regression following seizure episodes
Benefits of SCN1A Genetic Testing
Undergoing SCN1A gene analysis provides numerous advantages:
- Accurate Diagnosis: Confirms specific genetic etiology of seizure disorders
- Personalized Treatment: Guides medication selection based on genetic profile
- Family Planning: Provides recurrence risk information for future pregnancies
- Prognostic Information: Helps predict disease course and potential complications
- Early Intervention: Enables timely management strategies
- Genetic Counseling: Supports informed decision-making for affected families
Understanding Your Test Results
Your SCN1A genetic test results will fall into one of several categories:
- Positive Result: Indicates a pathogenic mutation in the SCN1A gene, confirming genetic predisposition to seizure disorders
- Negative Result: No mutation detected, though clinical correlation remains important
- Variant of Uncertain Significance: Genetic change identified with unknown clinical impact requiring further evaluation
- Carrier Status: Important for family members and reproductive planning
All results should be interpreted by qualified genetic specialists and neurologists who can provide comprehensive clinical context and management recommendations.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | SCN1A Gene Generalized Epilepsy with Febrile Seizures Plus Type 2 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Neurology and Genetics |
Pre-Test Requirements
Before scheduling your SCN1A genetic test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Testing Availability
We provide comprehensive SCN1A genetic testing services across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and neurological specialists ensures you receive expert care regardless of your location.
Take Control of Your Neurological Health
Understanding the genetic basis of seizure disorders can transform treatment approaches and improve quality of life. Our advanced NGS technology provides the most accurate genetic analysis available, helping patients and families navigate complex neurological conditions with confidence and clarity.
Ready to schedule your SCN1A genetic test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward personalized neurological care and genetic understanding.
