CHRNA2 Gene Epilepsy Nocturnal Frontal Lobe Type 4 NGS Genetic DNA Test
Comprehensive Genetic Testing for Nocturnal Frontal Lobe Epilepsy
The CHRNA2 Gene Epilepsy Nocturnal Frontal Lobe Type 4 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, specifically designed to identify mutations in the CHRNA2 gene that cause autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). This sophisticated testing methodology provides patients and healthcare providers with precise genetic information essential for accurate diagnosis and personalized treatment strategies.
What This Advanced Genetic Test Detects
Our NGS-based genetic test specifically targets the CHRNA2 gene, which encodes the alpha-2 subunit of the neuronal nicotinic acetylcholine receptor. Mutations in this gene disrupt normal neurotransmitter function in the brain, leading to the characteristic seizure patterns observed in nocturnal frontal lobe epilepsy. The test identifies:
- Point mutations in the CHRNA2 gene coding regions
- Small insertions and deletions affecting gene function
- Genetic variants associated with autosomal dominant inheritance patterns
- Specific mutations linked to sleep-related seizure activity
Who Should Consider CHRNA2 Genetic Testing
This specialized genetic test is particularly recommended for individuals experiencing:
- Recurrent nocturnal seizures occurring primarily during sleep
- Sudden awakenings with hypermotor movements or dystonic posturing
- Family history of sleep-related epilepsy disorders
- Unexplained nocturnal events that may be mistaken for parasomnias
- Resistance to conventional anti-epileptic medications
- Suspected genetic epilepsy syndromes with autosomal dominant inheritance
Significant Benefits of Genetic Testing
Undergoing CHRNA2 genetic testing provides numerous advantages for patients and their families:
- Accurate Diagnosis: Confirms or rules out genetic causes of nocturnal seizures
- Personalized Treatment: Enables targeted therapy based on specific genetic findings
- Genetic Counseling: Provides essential information for family planning decisions
- Prognostic Information: Helps predict disease course and potential complications
- Family Screening: Identifies at-risk relatives who may benefit from early intervention
- Reduced Diagnostic Uncertainty: Eliminates years of misdiagnosis and inappropriate treatments
Understanding Your Test Results
Our comprehensive genetic counseling support helps patients interpret their CHRNA2 test results:
- Positive Result: Indicates the presence of a pathogenic mutation in the CHRNA2 gene, confirming the genetic basis of nocturnal frontal lobe epilepsy
- Negative Result: Suggests that CHRNA2 mutations are not responsible for the patient’s symptoms, guiding further diagnostic evaluation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Provides information about inheritance patterns and risks to future generations
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | CHRNA2 Gene Epilepsy Nocturnal Frontal Lobe Type 4 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Take Control of Your Neurological Health Today
Don’t let uncertainty about nocturnal seizures impact your quality of life. Our CHRNA2 genetic testing provides the clarity needed for proper diagnosis and effective treatment planning. With our discounted price of only $500 USD, advanced genetic testing is more accessible than ever.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
Take the first step toward understanding your genetic predisposition to nocturnal frontal lobe epilepsy. Early and accurate diagnosis can significantly improve treatment outcomes and quality of life for you and your family members.
