ATP1A3 Gene DYT12 NGS Genetic DNA Test
Comprehensive Genetic Testing for Neurological Movement Disorders
The ATP1A3 Gene DYT12 NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise identification of mutations associated with DYT12 dystonia and related movement disorders. This advanced genetic analysis provides crucial insights for patients and healthcare providers seeking answers to complex neurological symptoms.
What Does the ATP1A3 Gene DYT12 Test Measure?
This sophisticated genetic test specifically targets the ATP1A3 gene, which encodes the alpha-3 subunit of the Na+/K+ ATPase enzyme. Mutations in this gene are directly linked to:
- Rapid-onset dystonia-parkinsonism (DYT12)
- Alternating hemiplegia of childhood (AHC)
- CAPOS syndrome (cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss)
- Recurrent encephalopathy with cerebellar ataxia
The test utilizes Next-Generation Sequencing (NGS) technology to comprehensively analyze the entire coding region of the ATP1A3 gene, detecting both known and novel mutations with exceptional accuracy.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Sudden onset of dystonia or parkinsonism symptoms
- Involuntary muscle contractions and abnormal postures
- Episodes of hemiplegia (one-sided weakness) that alternate sides
- Unexplained neurological deterioration following stress or illness
- Family history of movement disorders or neurological conditions
- Children with alternating weakness or paralysis episodes
- Progressive cerebellar ataxia with additional neurological features
Key Benefits of ATP1A3 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out ATP1A3-related disorders with high precision
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Prognostic Insights: Helps predict disease progression and potential complications
- Research Contribution: Contributes to ongoing neurological genetics research
- Peace of Mind: Reduces diagnostic uncertainty and facilitates appropriate care planning
Understanding Your Test Results
Your genetic test results will fall into one of several categories:
- Positive Result: Identifies a pathogenic mutation in the ATP1A3 gene, confirming the genetic basis of symptoms
- Negative Result: No mutation detected, suggesting symptoms may have other causes
- Variant of Uncertain Significance: Identifies a genetic change whose clinical significance requires further investigation
- Carrier Status: May identify individuals who carry the mutation but may not show symptoms
All results include comprehensive interpretation by our expert genetic counselors and neurologists, ensuring you receive clear explanations and appropriate next-step recommendations.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| ATP1A3 Gene DYT12 NGS Genetic DNA Test | $700 |
| Discount Price | $500 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Specialty: Neurologist
Department: Genetics
Method: NGS Technology
Disease Type: Neurological Disorders
Pre-Test Requirements
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, and many other cities. Our network of certified collection centers ensures easy access to this advanced genetic testing.
Take Control of Your Neurological Health
Don’t let unexplained neurological symptoms control your life. The ATP1A3 Gene DYT12 NGS Genetic DNA Test provides the clarity needed for proper diagnosis and management. Our team of genetic specialists and neurologists are ready to guide you through the testing process and help interpret your results.
Ready to begin your genetic testing journey? Contact us today at +1(267) 388-9828 to schedule your appointment or speak with our genetic counseling team. Take the first step toward understanding your neurological health with confidence and precision.
