ITM2B Gene Dementia Familial British Type NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Dementia
The ITM2B Gene Dementia Familial British Type NGS Genetic DNA Test represents a breakthrough in neurological genetic diagnostics, offering precise detection of mutations associated with familial British dementia. This progressive neurodegenerative disorder follows an autosomal dominant inheritance pattern, meaning a single copy of the mutated gene from either parent can cause the condition. Our advanced testing methodology provides families with crucial information for proactive healthcare management and informed decision-making.
What Does This Test Measure?
This specialized genetic test utilizes Next-Generation Sequencing (NGS) technology to comprehensively analyze the ITM2B (Integral Membrane Protein 2B) gene for specific mutations known to cause familial British dementia. The test detects:
- Point mutations in the ITM2B gene coding region
- Small insertions and deletions affecting protein function
- Genetic variants associated with amyloid deposition
- Pathogenic mutations linked to cerebral amyloid angiopathy
Who Should Consider This Test?
Clinical Indications and Symptoms
This genetic test is particularly recommended for individuals experiencing or concerned about:
- Progressive cognitive decline beginning in mid-adulthood
- Family history of early-onset dementia or neurological disorders
- Cerebellar ataxia and coordination difficulties
- Progressive spastic paraparesis symptoms
- Visual disturbances and ocular abnormalities
- Personality changes and behavioral alterations
- Memory impairment with progressive deterioration
Benefits of ITM2B Genetic Testing
Early Detection and Proactive Management
Undergoing ITM2B genetic testing provides numerous advantages for patients and families:
- Early Intervention Opportunities: Identify at-risk individuals before symptom onset
- Family Planning Guidance: Make informed reproductive decisions
- Personalized Treatment Approaches: Tailor neurological care based on genetic profile
- Psychological Preparation: Reduce uncertainty and anxiety about genetic risk
- Clinical Trial Eligibility: Access to specialized research and emerging therapies
- Comprehensive Risk Assessment: Understand inheritance patterns for family members
Understanding Your Test Results
Genetic Counseling and Interpretation
Our comprehensive results interpretation includes:
- Positive Result: Indicates presence of ITM2B mutation; requires neurological follow-up and family screening
- Negative Result: No detected mutation; significantly reduces but doesn’t eliminate dementia risk
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Professional Genetic Counseling: Essential for understanding implications and next steps
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | ITM2B Gene Dementia Familial British Type NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Specialty | Neurology |
| Department | Genetics |
| Method | NGS Technology |
| Disease Type | Neurological Disorders |
Pre-Test Requirements
Before scheduling your ITM2B genetic test, we recommend:
- Complete clinical history documentation of neurological symptoms
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications with healthcare provider
- Understanding of potential psychological impact of results
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and neurological specialists ensures comprehensive care regardless of your location.
Take Control of Your Neurological Health
Don’t let uncertainty about hereditary dementia risk affect your quality of life. Our ITM2B genetic testing provides the clarity needed for informed healthcare decisions and proactive management strategies. Early detection through genetic testing can significantly impact treatment outcomes and family planning decisions.
Ready to Schedule Your Test?
Contact our genetic specialists today to discuss your testing needs and schedule your appointment. Call us at +1(267) 388-9828 or book your consultation online. Our team is available to answer your questions about the ITM2B genetic test, insurance coverage, and what to expect throughout the testing process.
Take the first step toward understanding your genetic risk for familial British dementia. Book your comprehensive ITM2B genetic test today and gain valuable insights for your neurological health journey.
